The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

29333 Results

Name Source Clonality &
Isotype		 Host &
Formulation		 Method Reactivity Immunogen/
Epitope		 Specificity Availability
APP, APLP, AICD From labs (1)
anti-APP 369(Sam Gandy,Mount Sinai Alzheimer's Disease Research Center, NYC)References:Lane RF, 2010Vieira SI, 2010Pavlov PF, 2010Li H, 2010Gandy, 2010Zhang, 2009Liu, Y, 2009Hoe, 2009Tampellini, 2007White, 2006Puglielli, 2001Li, 2003 polyclonal
 Rabbit
 - Human, Mouse immunogen = entire cytoplasmic tail of APP(paper) C-terminal APP -
APP, APLP, AICD From manufacturers (3)
Biosource Invitrogen polyclonal
 Goat
(liquid, whole serum, azide, unconj.)		 - Human immunogen = synthetic peptide (G Y E N P T Y K F F E Q M Q N) corresp. to aa sequence 681-695 of C terminus of human APP C-terminus of APP(100kDa), may cross-react with APLP2 -
Chemicon and Upstate are Millipore monoclonal
IgG1		 Mouse
(liquid, PBS, azide, purified)		 - Fish (various), Dog, Pig, Human, Monkey, Mouse, Rat immunogen = purified rhN-terminal epitope (aa 66-81) on the pre-A4 molecule, fusion protein human pre-A4 APP; recognizes all three isoforms of APP, immature ~110kDa, sAPP ~120kDa, and mature ~130kDa; cross reacts with APLP2 -
Chemicon and Upstate are Millipore monoclonal
IgG1		 Mouse
(lyophilized, ascites)		 - Human, Rat immunogen = C-terminal fragment APP643-695/Jonas full-length APP and selectively with the cytoplasmic C-terminal fragment of APP 643-695 -
Actin Related From manufacturers (2)
Sigma Aldrich monoclonal
IgG2a		 Mouse
(liquid, purified, PBS, azide)		 - Various species immunogen = synthetic actin CN-terminal peptide, Ser-Gly-Pro-Ser-Ile- Val-His-Arg-Lys-Cys-Phe, attached to a Multiple Antigen Peptide (MAP) backbone 42 kDa actin; recognizes an epitope located on the C-terminal end of actin conserved in all actin isoforms -
Sigma Aldrich monoclonal
IgG1		 Mouse
(aqueous solution, purified, PBS, azide)		 - Bovine, Cat, Dog, Chicken, Carp, Sheep, Pig, Human, Guinea Pig, Mouse, Rat, Drosophila immunogen = slightly modified β-cytoplasmic actin N-terminal peptide, Ac-D D D I A A L V I D N G S G L, KLH conj. detects 42 kDa beta-actin -
Akt and Serine/Threonine Kinases From manufacturers (2)
Cell Signaling monoclonal
IgG		 Rabbit
(liquid, HEPES, NaCl, BSA, glycerol)		 - Human, Mouse, Rat Immunogen = synthetic phospho-peptide corresp. to residues around Thr389 of human p70 S6 kinase detects endogenous levels of p70 S6 kinase only when phosphorylated at threonine 389; also detects p85 S6 kinase when phosphorylated at the analogous site (Thr412), and possibly S6KII phosphorylated at Thr401 -
Cell Signaling polyclonal
 Rabbit
(liquid, HEPES, NaCl, BSA, glycerol, azide)		 - Human, Monkey, Mouse, Rat Immunogen = synthetic phospho-peptide corresp. to residues around Thr389 of human p70 S6 kinase detects endogenous levels of p70 S6 kinase only when phosphorylated at threonine 389; also detects p85 S6 kinase when phosphorylated at the analogous site (Thr412), and possibly S6KII phosphorylated at Thr401 -
Amyloid-β From labs (3)
1E8(Paul Cutler,SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, Harlow, Essex, UKpaper: Cutler, et al, l997) monoclonal
 Mouse
 - Bovine, Human immunogen = the derived peptide sequence aa. 13–22, (epitope at aa. 18-22, VFFAE) of beta amyloid reacts with the N terminal of amyloid-beta; recognizes Aβ[1–40], Aβ[1–42] and Aβ[1–43] -
anti-amyloid beta 21F12(Frederique Bard,Elan Pharmaceuticals, So. San Francisco, CA Paper: Johnson-Wood, et al, PNAS February 18, 1997)References:Siderowf, 2010Okereke, 2009Serneels, 2009Brody, 2008Holmes, 2008Shankar, 2008Roberson, 2007Salehi, 2006 monoclonal
 Unknown Host
 - - immunogen = synthetic peptide fragment derived from different regions of amyloid-beta and coupled to a carrier protein amyloid-beta; recognizes amino acids 33-42; negligible crossreactivity (1–40 -
Elan Pharmaceuticals monoclonal
 Mouse
 - Human, Mouse immunogen = synthetic peptide fragment conjugated to sheep anti-mouse immunoglobulin; epitope at aa 1-5 within Aβ42 Aβ (recognizes amino acids 1-5). Does not recognize secreted APP or APP-FL. Detects only Aβ species with amino-terminal aspartic acid.   -
Amyloid-β From manufacturers (3)
Cell Signaling polyclonal
 Rabbit
(liquid, HEPES, NaCl, BSA, glycerol, affinity purified)		 - Bovine, Human, Rat immunogen = synthetic peptide corresp. to residues at the N-terminus of human β-Amyloid peptides detects several isoforms of β-amyloid peptide (Abeta), such as Abeta-40, Abeta-42 etc, regardless of phosphorylation state -
BioLegend monoclonal
IgG1		 Mouse
(biotinylated IgG, PBS, no preservatives or carrier proteins)		 - Human the epitope lies within amino acids 3-8 of beta amyloid (EFRHDS) reactive to aa 1-16 Amyloid β; reacts to the abnormally processed isoforms, as well as precursor forms Available from BioLegend
Innogenetics kit
 Unknown Host
(well standardized multiparameter bead-based immunoassay for the simultaneous quantification of human ß-amyloid in plasma using xMAP® (registered trademark of Luminex Corp)technology)		 - Human Uses 3D6 antibody;3D6 selectively binds Aß peptides with a free aminogroup at Asp1 (epitope 1–5) for simultaneous quantification of different forms of β-amyloid in blood, with check for matrix interference -
Astrocyte Markers From manufacturers (1)
Chemicon and Upstate are Millipore monoclonal
IgG1		 Mouse
(ascites, azide)		 - Bovine, Rabbit, Chicken, Pig, Human, Mouse, Rat purified GFAP from porcine spinal cord. recognizes ~50 kDa band; astrocytes and Bergmann glia cells, glioma and glial cell derived tumors -
CD11b, Integrins From manufacturers (6)
Chemicon and Upstate are Millipore monoclonal
IgG2b		 Rat
(liquid, purified, PBS, azideAlso available Phycoerythrin conjugated, CBL1313P)		 - Mouse immunogn = B10 mouse spleen cells enriched with T cells specific to CD11b; recognizes a differentiation antigen situated on mononuclear phagocytes and granulocytes; the expression of this antigen (Mac 1) increases during monocyte maturation -
Chemicon and Upstate are Millipore monoclonal
IgG2a		 Mouse
(liquid, protein-A affinity purified, PBS, azide.Also available protein-G purified, PBS, no preservatives, CBL1512Z, or FITC conjugated, CBL1512F)		 - Rat immunogn = rat peritoneal macrophages recognizes most macrophages (including resident peritoneal and activated macrophages), Kupffer cells, but only about 35% of alveolar macrophages; also labels dendritic cells extensively, granulocytes and cells with the morphology of microglia in brain -
Chemicon and Upstate are Millipore monoclonal
IgG1		 Mouse
(liquid, purified, PBS, BSA, azide.Also available Phycoerythrin conjugated, CBL145P)		 - Baboon, Human, Monkey immunogn = synovial cells and human monocytes reacts with the integrin heterodimer of 165 kDa which comprises the CD11b receptor -
Chemicon and Upstate are Millipore monoclonal
IgG2b		 Rat
(liquid, protein-G purified, PBS, no preservatives)		 - Human, Mouse immunogn = T cell enriched splenocytes from B10 mice recognizes the murine alphaM integrin chain; stains polymorphonuclear cells, monocytes and NK cells -
Chemicon and Upstate are Millipore monoclonal
IgG1		 Mouse
(liquid, ascites, protein-A affinity purified, PBS, azide.)		 - Rat immunogn = spleen cell homogenate with FCA recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes; recognizes small ramified (micro) glial cells in the central nervous system -
Chemicon and Upstate are Millipore monoclonal
IgG2a		 Mouse
(liquid, purified, PBS, azide)		 - Human immunogn = leukemic cells of CML specific to CD11b; reacts with the CR3-receptor of inactivated C3b component of complement (C3bi) -
CD_ except CD11b, CD40, CD45 and CD147 From manufacturers (1)
AbD Serotec monoclonal
IgG2a		 Rat
(liquid, protein-G affinity purified IgG from supernatant, PBS, azide)		 - Mouse - recognizes the murinehomologue of the human macrophage glycoprotein CD68 -
CREB, cAMP, CBP From manufacturers (1)
Cell Signaling monoclonal
IgG		 Rabbit
(liquid, Hepes, NaCl, BSA, glycerol, Protein A and affinity purified)		 - Human, Monkey, Mouse, Rat immunogen = synthetic phospho-peptide (KLH-coupled) corresp. to residues surrounding Thr71 of human ATF-2 (CRE-BP1) reacts with endogenous levels of ATF-2 only when phosphorylated at threonine 71; no cross-reaction with phosphorylated c-Jun, CREB or other transcription factors; reacts with both Thr69/Thr71 dually phosphorylated ATF-2 and Thr71 singly phosphorylated ATF-2 equally well -
Caspases From manufacturers (1)
Cell Signaling polyclonal
IgG		 Rabbit
(liquid, protein-A, affinity purified)		 - Bovine, Human, Monkey, Mouse, Rat immunogen = synthetic peptide (KLH-coupled) corresp. to amino-terminal residues adjacent to Asp175 of human caspase-3 detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3 resulting from cleavage adjacent to Asp175; does not recognize full length caspase-3 or other cleaved caspases -
Cell Cycle From manufacturers (4)
Upstate and Chemicon are Millipore polyclonal
IgG		 Rabbit
(liquid, antiserum)		 - Avian (various), Human, Mouse, Rat immunogen = synthetic peptide corresponding to aa 35-51 (TPQHYPSFG VTSIPNYN) of human Fyn detects Fyn p59 -
Cell Signaling polyclonal
 Rabbit
(liquid, protein A and peptide affinity purified, HEPES, saline, BSA, glycerol)		 - Chicken, Human, Mouse, Rat, Xenopus immunogen = synthetic phosphopeptide corresponding to residues surrounding Tyr416 of human Src detects endogenous levels of Src only when phosphorylated at Tyr416; antibody may cross-react with other Src family members such as Yes, Fyn, Fgr and Yrk when phosphorylated at the equivalent sites -
Cell Signaling monoclonal
IgG		 Rabbit
(liquid, protein A and peptide affinity purified, HEPES, saline, BSA, glycerol, azide)		 - Human, Mouse, Rat immunogen = synthetic phosphopeptide corresponding to residues surrounding Tyr416 of human Src detects endogenous levels of Src only when phosphorylated at Tyr416; antibody may cross-react with other Src family members such as Yes, Fyn, Fgr and Yrk when phosphorylated at the equivalent sites -
Upstate and Chemicon are Millipore monoclonal
IgG		 Mouse
(frozen liquid, protein G purified, Tris-glycine, saline, azide)		 - Bovine, Human immunogen = recombinant human p35 recognizes 33 kDa p35 -
G-protein Related From manufacturers (1)
Synaptic Systems monoclonal
IgG1		 Mouse
(purified IgG, lyophilized)		 - Cow, Human, Hamster, Mouse, Rat immunogen = purified Rab-GDI of bovine brain recognizes Rab-GDI-α and -β; immunoprecipitates Rab-GDI complexes -
GABA & Related From manufacturers (2)
Synaptic Systems monoclonal
IgG1		 Mouse
(purified IgG, lyophilized)		 - Human, Mouse, Rat immunogen = purified recombinant doublet of E-Domain (aa 307 - 735) (epitope: C6 domain located in the first half of the E-domain) detects all splice variants that contain a complete E-domain including the C6 domain -
Synaptic Systems polyclonal
 Rabbit
(affinity purified with the immunogen, lyophilized)		 - Human, Monkey, Mouse, Rat Immunogen = synthetic peptide AEPPVEGDIHYQR (aa residues 75 - 87 in rat) coupled to KLH Specific for vGAT -
GSK-3α & GSK-3β From manufacturers (2)
Santa Cruz polyclonal
IgG		 Goat
(liquid, PBS, gelatin, azide, affinity purified;also available as rabbit, sc-11757-R)		 - Fish (various), Zebra, Human, Mouse, Rat, Xenopus Immunogen = short amino acid sequence containing phos-phorylated Ser9 of human GSK-3β Ser9 phosphorylated GSK-3β -
Chemicon and Upstate are Millipore monoclonal
IgG		 Rabbit
(liquid, Tris-glycine, saline, gl;ycerol, azide, BSA)		 - Human Immunogen = phospho-specific peptide corresponding to residues surrounding Ser9 of human GSK3 β detects only GSK3 β phosphorylated on Ser9 -
Glutamate Receptor & Related From manufacturers (5)
Phospho- solutions polyclonal
 Rabbit
(liquid, HEPES, NaCl, BSA, glycerol, affinity purified)		 - Human, Mouse, Rat Immunogen = phosphopeptide corresp. to aa residues surrounding the anti-phospho-Try1472 of NMDA Receptor NR2B ~180 NMDA Receptor NR2B-subunit phosphorylated at Tyr1472, also labels ~65k and ~115k. -
Chemicon and Upstate are Millipore polyclonal
IgG		 Rabbit
(liquid, tris-glycine saline, azide, Protein G purified)		 - Bovine, Dog, Human, Monkey, Mouse, Rat Immunogen = peptide comprising the C-terminal 20 aa of mouse NR2B (K F N G S S N G H V Y E K L S S I E S D V) NR2B -
Chemicon and Upstate are Millipore monoclonal
IgG		 Mouse
(liquid, purified IgG, Tris-glycine, saline, azide)		 - Human, Mouse, Rat Immunogen = His-tag fusion protein corresponding to residues 834-938 of rat NR1A; epitope maps to a region (a.a. 834-864) common to all NR1 isoforms detects NMDAR1, 130 kDa by WB -
Chemicon and Upstate are Millipore polyclonal
 Rabbit
(liquid, unpurified serum, azide)		 - Mouse, Rat immunogen = GST-tagged recombinant protein corresponding to rat NR2A at the C-terminus recognizes NR2A (~176 kDa) at the C-terminus -
Chemicon and Upstate are Millipore polyclonal
IgG		 Rabbit
(liquid, tris-glycine saline, glycerol, azide, Protein A purified)		 - Mouse, Rat immunogen = 6His-tagged fusion protein corresp.to aa1265-1464 of mouse NMDA receptor 2A (NR2A). NR2A (170 kDa) -
Heat Shock Proteins From manufacturers (3)
Synaptic Systems monoclonal
IgG1		 Mouse
(purified IgG, lyophilized)		 - Cow, Human, Hamster, Mouse, Rat immunogen = purified bovine ATPase (epitope between aa 391-546) detects Hsp70, specific for uncoating ATPase -
Pierce Thermo Scientific monoclonal
IgG2a		 Rat
(liquid, Protein G purified, PBS)		 - Bovine, Dog, Ovine, Porcine, Rabbit, Chicken, Various species, Human, Monkey, Guinea Pig, Hamster, Mouse, Rat immunogn = full length, native Hsc70 protein purified from sodium arsenite treated heat-resistant variants of Chinese hamster cells specific for Hsc70 -
Stressgen Enzo Life Sciences monoclonal
IgG2a		 Rat
(liquid, PBS, azide, glycerol, affinity purified)		 - Bovine, Dog, Chicken, Turtle, Sheep, Pig, Human, Monkey, Guinea Pig, Hamster, Mouse, Rat immunogen = native hamster Hsc70 (Hsp73) recognizes ~73 kDa Hsc70 -
Kinases From manufacturers (3)
Acris Antibodies polyclonal
 Rabbit
(liquid, prrified Ig fraction, PBS, azide, affinity purified)		 - Human, Mouse, Rat Immunogen = a 28 amino acid peptide from near the center of humanBRSK1 recognizes BRSK1 -
Abcam polyclonal
IgG		 Rabbit
(liquid, affinity purified, glycerol, BSA, PBS, azide)		 - Human, Mouse immunogen = Synthetic peptide (Human) derived from the region of JNK 1 + 2 that contains threonine 183 and tyrosine 185, based on the human sequence (conservd among many species) detects JNK 1 + 2 phosphorylated at threonine 183 and tyrosine 185 -
BD Transduction monoclonal
IgG1		 Mouse
(liquid, affinity purified)		 - Dog, Frog, Human, Mouse, Rat Immunogen = aa 353 to 486 from rat CASK detects CASK -
MAPKs From manufacturers (3)
Santa Cruz polyclonal
IgG		 Rabbit
(liquid, PBS, gelatin, azide, afffinity purified)		 - Chicken, Zebra fish, Human, Mouse, Rat, Xenopus Immunogen = peptide mapping at the C-terminus of rat ERK 2 detects ERK 2 p42, and to a lesser extent, ERK 1 p44 -
Santa Cruz polyclonal
IgG		 Rabbit
(liquid, PBS, gelatin, azide, available as phycoerythrin conjugate sc-153 PE)		 - Chicken, Zebra fish, Human, Mouse, Rat, Xenopus, Drosophila Immunogen = peptide mapping subdomain XI (r) of rat ERK 2 detectss ERK 2 p42, and to a lesser extent, ERK1 p44 -
Santa Cruz monoclonal
IgG2a		 Mouse
(liquid, PBS, gelatin, azide, available conj. phycoerythrin sc-7838 PE, agarose sc-7838 AC, fluorescein sc-7383 FITC or rhodamine sc-7383 TRITC)		 - Human, Mouse, Rat Epitope corresponding to a sequence containing phosphorylated Tyr-204 of human ERK ERK1 and ERK2 phosphorylated at Tyr-204 -
MAPs From manufacturers (3)
Sigma Aldrich monoclonal
IgG1		 Mouse
(ascites fluid, azide)		 - Bovine, Quail, Salamander, Human, Mouse, Rat, Xenopus immunogen = bovine MAP2 MAP2a and MAP2b; not MAP2c, MAP1, MAP5, tubulin, or tau -
Chemicon and Upstate are Millipore monoclonal
IgG1		 Mouse
(purified IgG, phosphate buffer, saline, azide.Also available as AlexaFluor® 488 conjugate)		 - Bovine, Chicken, Quail, Human, Mouse, Rat, Xenopus immunogen = bovine brain microtubule protein MAP2 in neuronal cell bodies and dendrites -
Chemicon and Upstate are Millipore polyclonal
 Rabbit
(liquid, purified, PBS, azideAlso availanle ready to use, Cat# IHCR1004-6)		 - Human, Mouse, Rat immunogen = purified rat brain MAP MAP2a and MAP2b and (lesser) MAP2c and MAP2d -
Microglial Markers From manufacturers (2)
Wako Chemicals polyclonal
 Rabbit
(sera, affinity purified, TBS, no preservatives or stabilizers)		 - Human, Mouse, Rat Immunogen = synthetic peptide corresponding to the C-terminus of Iba-1 (Ionized calcium binding adaptor molecule 1) Microglia and macrophages, but no cross reactivity with neurons and astrocytes -
Wako Chemicals polyclonal
 Rabbit
(sera, affinity purified, TBS, no preservatives or stabilizers)		 - Human, Mouse, Rat Immunogen = synthetic peptide corresponding to the C-terminus of Iba-1 (Ionized calcium binding adaptor molecule 1) Microglia and macrophages, but no cross reactivity with neurons or astrocytes -
Motor Proteins From manufacturers (1)
Chemicon and Upstate are Millipore monoclonal
IgG2b		 Mouse
(liquid, phosphate buffer, saline, azide)		 - Mammal (various), Chicken, Sea Urchin, Squid, Human, Mouse, Rat, Clam immunogen = bovine brain kinesin, epitope at aa 420-445 Reacts with the heavy chain of kinesin near the N-terminus -
Neurofilaments From manufacturers (1)
Cell Signaling monoclonal
IgG1		 Mouse
(liquid, purified Ig, azide)		 - Human, Mouse, Rat immunogen = rat neurofilament detects endogenous levels of total Neurofilament-H protein, 180-220 kDa -
Neuronal Markers From manufacturers (1)
Chemicon and Upstate are Millipore monoclonal
IgG1		 Mouse
(liquid, purified Ig, phosphate buffer, NaCl, azideAlso available prediluted, IHR1001-6)		 - Avian (various), Primate (various), Chicken, Salamander, Ferret, Pig, Human, Mouse, Rat immunogen = purified cell nuclei from mouse brain reacts with most neuronal cell types; is an excellent marker for neurons in primary cultures and in retinoic acid-stimulated P19 cells -
Nitric Oxide From manufacturers (3)
BD Transduction monoclonal
IgG2a		 Mouse
(aqueous buffered solution containing BSA, glycerol, azide, affinity purified, FITC conj.)		 - Mouse immunogen = mouse iNOS aa. 961-1144 recognizes ~130 kDa iNOS -
BD Transduction monoclonal
IgG1		 Mouse
(aqueous buffered solution containing BSA, glycerol, azide)		 - Mouse immunogen = mouse iNOS aa. 961-1144 at C-terminal recognizes ~130 kDa iNOS; reported to cross-react with nNOS and eNOS -
BD Transduction monoclonal
IgG2a		 Mouse
(aqueous buffered solution containing BSA, glycerol, azide)		 - Mouse immunogen = mouse iNOS aa. 961-1144 recognizes ~130 kDa iNOS -
Organelles From manufacturers (2)
BD Transduction monoclonal
IgG1,κ		 Mouse
(aquaeous buffered solution, BSA, glycerol, azide, affinity purified)		 - Dog, Human, Mouse, Rat immunogen = Rat GM130, aa. 869-982 recognizes GM130, 130 kDa -
Santa Cruz monoclonal
IgG1		 Mouse
(liquid, PBS, azide, gelatin.Also available as sc-18822 PE or sc-18822 FITC conjugates for FC, and Alexa Fluor® for FC or IF)		 - Human immunogen = adherentspleen cells of human origin detects LAMP-2 -
PSD95 From manufacturers (1)
Pierce Thermo Scientific monoclonal
IgG2a		 Mouse
(liquid, purified, PBS, azide)		 - Mouse, Rat, Xenopus immunogen = purified recombinant rat PSD-95 detects ~95 kDa PSD protein -
Phosphatases From manufacturers (2)
Santa Cruz monoclonal
IgG1		 Mouse
(liquid, PBS, gelatin, azide)		 - Mouse, Rat immunogen = an 18 amino acid sequence mapping at the N-terminus of STEP46 of rat origin for detection of all known isoforms of STEP of mouse and rat origin -
Cell Signaling monoclonal
IgG		 Rabbit
(liquid, HEPES, saline, BSA, glycerol, azide)		 - Human, Monkey, Mouse, Rat, Drosophila immunogen = a synthetic peptide corresp. to the sequence of human PP2A C subunit protein detects endogenous levels of PP2A catalytic subunit protein (both alpha and beta isoforms); does not cross-react with other PP2A subunits -
Protein Trafficking From manufacturers (3)
Abcam polyclonal
IgG		 Goat
(liquid, affinity purified, Tris, BSA, azide)		 - Human immunogen = synthetic peptide: S P E S E G P I Y E G L I L, corresp. to C terminal aa 783-796 of Human Vps35 detects Vps35 (~90 kDa, WB) -
Abcam polyclonal
IgG		 Rabbit
(liquid, affinity purified, Thimerosal, glycerol, Tris glycine)		 - Human immunogen = synthetic peptide corresponding to a region within amino acids 733-796 of human VPS35 detects Vps35 -
Abcam monoclonal
IgG2a, κ		 Mouse
(liquid, PBS, no preservative, protein G purified)		 - Human immunogen = recombinant fragment corresp. to aa 697-797 of human VPS35 Vps35 -
SOD From labs (1)
C4F6Makoto Urushitani, Department of Anatomy and Physiology, Laval University Research Centre, Centre Hospitalier de l'Université Laval, Québec, Canada PaperReference: Bosco DA, 2010 monoclonal
 Mouse
(liquid)		 - Human, Mouse Immunogen = recombinant G93A SOD1 protein recognizes the G93A SOD1 and to a lower extent other mutant SOD1 forms, including G37R and G85R; very poor reactivity to the wild type SOD1 -
SOD From manufacturers (3)
the Binding Site polyclonal
 Sheep
(liquid, Glycine Buffered Saline (GBS), EACA, EDTA, bnzamidine, azide)		 - Human Immunogen = human SOD Cu/Zn, Purified from Erythrocytes reacts with human SOD Cu/Zn -
Calbiochem EMD Biosciences polyclonal
IgG		 Sheep
(liquid, glycine-buffered saline, EDTA, azide, e-amino-n-caproic acid, benzamidine)		 - Human, Monkey, Mouse, Rat Immunogen = highly purified superoxide dismutase (SOD) Cu/Zn enzyme from human erythrocytes Recognizes Cu/Zn SOD in red blood cells. Does not cross-react with Mn SOD. -
Sigma Aldrich monoclonal
IgG1		 Mouse
(liquid, ascites, azide)		 - Dog, Human, Rat immunogen = recombinant human Cu-Zn SOD recognizes natural and recombinant CuZn SOD -
Sortilins From manufacturers (2)
BD Transduction monoclonal
IgG2a		 Mouse
(Aqueous buffered solution, BSA, glycerol, azide, affinity purifiedSee also Cat# 612663 for IH)		 - Human, Mouse, Rat Immunogen = human LR11 (aa. 1220-1337) detects LR11; 250 kDa by WB -
BD Transduction monoclonal
IgG2a		 Mouse
(Aqueous buffered solution, BSA, glycerol, azide, affinity purified)		 - Human, Mouse, Rat, Drosophila Immunogen = human LR11 (aa. 1220-1337) detects LR11; detects a band of ~250 kDa in S2 cells and a 250 kDa plus a 200 kDa in rat cerebrum and Drosophila embryos -
Synaptic Vesicle Fusion From manufacturers (9)
Synaptic Systems monoclonal
IgG1		 Mouse
(purified IgG or ascites, lyophilized)		 - Various vertebrate, Human, Mouse, Rat immunogen = recombinant full length rat SNAP 25 (epitope in the conserved N-terminal portion of the protein, aa 20-40 ) specific for SNAP 25; recognizes splice variants SNAP 25A and B, and the Botulinum neurotoxin A and E cleavage products -
Synaptic Systems monoclonal
IgG1		 Mouse
(lyophilized, purified IgG)		 - Human, Hamster, Mouse, Rat immunogen = synthetic peptide (SATAATVP PAAPAGEG) corresponding to residues 2-17 of rat Synaptobrevin 2, coupled to KLH specific for Synaptobrevin2/ VAMP2; no cross with VAMP1 or VAMP3 -
Synaptic Systems monoclonal
IgG1		 Mouse
(lyophilized, purified IgGAlso available as fluorescence labeled, 101011C3 and 101011C5,or biotin labeled, 101011BT)		 - Mammal (various), Human, Mouse, Rat immunogen = electro phoretically purified synaptophysin, (epitope in cytoplasmic tail) Detects synaptophysin 1 with no cross-reactivity towards other synaptophysins -
Synaptic Systems monoclonal
IgG1		 Mouse
(purified IgG or ascites, lyophilized.Also available fluorescence-labeled, 110011C3)		 - Mammal (various), Chicken, Zebra fish, Human, Mouse, Rat immunogen = recombinant protein containing the N-terminal part of rat syntaxin 1 specific for Syntaxin 1A and B with preference for syntaxin 1B -
Synaptic Systems polyclonal
 Rabbit
(antiserum, lyophilized.)		 - Human, Mouse, Rat, Electric ray immunogen = synthetic peptide KYLPGPLQDMFKK (aa 122 - 134 in human) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue recognizes complexin 1 and 2 -
BD Transduction monoclonal
IgG1		 Mouse
(aqueous buffered solution, BSA, glycerol, azide)		 - Human, Mouse, Rat immunogen = Rat Munc-18-1, aa. 381-567, near the C-terminal recognizes Munc-18, 68 kDa -
BD Transduction monoclonal
IgG2b		 Mouse
(aqueous buffered solution, BSA, glycerol, azide)		 - Mouse, Rat - recognizes rabphilin-3A, ~75 kDa -
Synaptic Systems monoclonal
IgG1		 Mouse
(purified IgG, lyophilized)		 - Various vertebrate, Human, Mouse, Rat immunogen = recombinant full length rat Rab 3a (epitope localized to a stretch of amino acids in the middle of the molecule, aa 95 - 151) specific for all four Rab 3 isoforms a, b, c d -
None monoclonal
IgG1		 Mouse
(ascites fluid, azide)		 - Various animal immunogen = whole, unaltered SNAP-25 (epitope lies in the amino end of the C-terminal of SNAP-25) detects SNAP 25; visualizes synapse-rich areas of brain and retina in a wide variety of mammalian and non-mammalian species Discontinued
Synucleins From labs (1)
α-Synuclein LB509(Takeshi Iwatsubo, Department of Neuropathology & Neuroscience, Grad. School of Pharmaceutical Sciences, University of Tokyo)Also see Abcam ab27766, SantaCruz sc-58480, and others.References:Tokuda, 2010Tsika, 2010Xu, 2002 monoclonal
 Mouse
 - Human (epitope at the C terminus of the protein, residues 115-122) detects α-Synuclein, C-terminal -
Synucleins From manufacturers (4)
Santa Cruz monoclonal
IgG1		 Mouse
(liquid, PBS, gelatin, azide)		 - Human immunogen = aa 121-125 of human α-synuclein α-synuclein, 19kDa -
Santa Cruz polyclonal
IgG		 Rabbit
(liquid, PBS, gelatin, azide)		 - Human, Mouse, Rat immunogen = recombinant protein corresp. to aa 1-140 representing full-length human α-synuclein recognizes α/ β/ γ-synuclein -
Santa Cruz monoclonal
IgG1		 Mouse
(liquid, PBS, gelatin, azide)		 - Human immunogen = Lewy bodies of human origin recognizes α-synuclein, 19kDa -
BD Transduction monoclonal
IgG1		 Mouse
(liquid, BSA, glycerol, azide, positive control)		 - Human, Mouse, Rat immunogen = aa. 15-123 of rat synuclein-1 Synuclein-1,mol. wt. = 19kDa -
Tau From labs (2)
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
IgG1		 Mouse
 - Human, Mouse epitope at aa102–140 recognizes total tau -
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
IgM		 Mouse
(IC, IF, IH, IP, WB)		 - Human Tau phosphorylated at threonine-231; also conformation-sensitive. Tau phosphorylated at threonine-231; also conformation-sensitive. Not reactive to normal tau. The TG3 epitope is expressed in mitotic cells but not in quiescent cells, suggesting that mitotic phosphoepitopes may lead to conformational changes. -
Tau From manufacturers (4)
Pierce Thermo Scientific monoclonal
IgG1κ		 Mouse
(serum-free supernatant, affinity purified, no carrier or preservative. Also available Biotin conj, MN-1000B)		 - Bovine, Human immunogen = purified human tau, between aa 159 and 163, (PPGQK) tau and PHF tau from human and bovine brain -
Pierce Thermo Scientific monoclonal
IgG1κ		 Mouse
(purified, no carrier or preservative)		 - Human immunogen = aa. around phosphorylated Thr231 detects Tau doubly phosphorylated at Thr231 and Ser235; weak recognition of phosphorylation at Thr231 only -
Biosource Invitrogen monoclonal
IgG1		 Mouse
(ascites, affinity purified BSA, azide, unconj.)		 - Cow, Sheep, Human, Mouse, Rat immunogen = purified bovine microtuble associated proteins; epitope in middle region of tau tau proteins ranging from 45-68 kDa, not other MAPs or tubulin; tangles marker; reacts with non-phosphor. and phosphor. tau -
Autogen Bioclear kit
 Mouse
(solid-phase enzymeimmunoassay, uses monoclonal AT120 for capture, HT7 and BT2 for incubation, streptavidin)		 - Human - tau in cerebrospinal fluid -
Tools From manufacturers (3)
Roche Applied Science monoclonal
IgG1, κ		 Mouse
(mixture of two monoclonal antibodies, supplied as a white lyophilizate)		 - - - can be used to verify the expression of Green Fluorescent Protein (GFP) and GFP fusion proteins; recognizes both wild-type and mutant forms of GFP -
BioLegend monoclonal
IgG1		 Mouse
(liquid, purified, PBS, glycerol, thimerosal.Also available as ascites, MMS-101R, Biotin, BIOT-101L,FITC, FITC-101L,AFC, AFC-101P,Alexa Fluor® 488, A488-101L Alexa Fluor® 594, A594-101L)		 - - immunogen = the twelve amino acid peptide CYPYDVPDYASL recognizes the influenza hemagglutinin epitope (YPYDVPDYA) located in the middle of protein sequences as well as at the N- or C-terminus Available from BioLegend
Santa Cruz monoclonal
IgG1		 Mouse
(gelatin, PBS, azideAvailable as phycoerythrin, agarose, HRP, fluorescein, rhodamine or biotin conj, and Alexa Fluor® 405, 488 or 647)		 - Human, Mouse, Rat immunogen = peptide corresp. to aa 408-439 within the C-terminal domain of c-Myc of human origin detects c-Myc p67 -
Tubulin From manufacturers (2)
R&D Systems monoclonal
IgG2A		 Mouse
(Protein A or G purified from hybridoma culture supernatant, PBS, BSA, biotinylated, lyophilized)		 - Mammal (various), Chicken immunogen = microtubules derived from rat brain detects mammalian and chicken neuron­specific β­III tubulin but not other β­tubulin isotypes -
Sigma Aldrich monoclonal
IgG1		 Mouse
(liquid, purified IgG, PBS, BSA, azideAlso available as ascites and as FITC conj.)		 - Bovine, Chicken, Human, Mouse immunogen = purified chick brain tubulin (epitope at aa 426-430) recognizes an epitope located at the C-terminal end of alpha-tubulin -
p38 MAPK & MAPK11-14 From manufacturers (3)
Cell Signaling monoclonal
IgG		 Rabbit
(liquid, HEPES, NaCl, BSA, glycerol)		 - Mink, Human, Monkey, Mouse, Rat Immunogen = synthetic phospho-peptide corresp. to residues surrounding Thr180/Tyr182 of human p38 MAP kinase conj. to KLH Detects endogenous levels of p38 MAP kinase only when dually phosphorylated at Thr180 and Tyr182. Does not cross-react with the phosphorylated forms of either p42/44 MAPK or SAPK/JNK -
Cell Signaling polyclonal
 Rabbit
(liquid, HEPES, NaCl, BSA, glycerol, Protein A and peptide affinity purified)		 - Pig, Human, Monkey, Mouse, Rat, S. cerevisiae, Drosophila Immunogen = synthetic phospho-peptide corresp. to residues around Thr180/Tyr182 of human p38 MAP kinase Detects endogenous levels of p38 MAP kinase only dually phosphorylated at Thr180 and Tyr 182. Does not cross react with phosphorylated forms of p42/44 MAPK or SAPK/JNK -
Cell Signaling polyclonal
 Rabbit
(liquid,, HEPES, NaCl, BSA, glycerol, protein A and peptide affinity purified)		 - Human, Monkey, Guinea Pig, Mouse, Rat Immunogen = synthetic peptide derived from the seq. of human MAP kinase, coupled to KLH Detects endogenous levels of total p38 MAP kinase protein. Does not cross-react with p38δ, JNK/SAPK or p44/42 MAP kinase -