Antibody

Amyloid β [1-42] and Aβ [1-40]

Tools

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Clonality: kit
Host: Unknown Host
Source: Innogenetics
cat# 80933
INNO-BIA
blood ß-amyloid kit
Leaflet
References:
Siderowf, 2010
Fagan, 2009
Lambert, 2009
Formulation: well standardized multiparameter bead-based immunoassay for the simultaneous quantification of human ß-amyloid in plasma using xMAP® (registered trademark of Luminex Corp)technology
Reactivity:
Reacts in: Human

Immunogen/Epitope

Uses 3D6 antibody;
3D6 selectively binds Aß peptides with a free amino
group at Asp1 (epitope 1–5)

Specificity

for simultaneous quantification of different forms of β-amyloid in blood, with check for matrix interference

Note

see details

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References

Paper Citations

  1. Siderowf A, Xie SX, Hurtig H, Weintraub D, Duda J, Chen-Plotkin A, Shaw LM, Van Deerlin V, Trojanowski JQ, Clark C. CSF amyloid {beta} 1-42 predicts cognitive decline in Parkinson disease. Neurology. 2010 Sep 21;75(12):1055-61. PubMed.
  2. Fagan AM, Mintun MA, Shah AR, Aldea P, Roe CM, Mach RH, Marcus D, Morris JC, Holtzman DM. Cerebrospinal fluid tau and ptau181 increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease. EMBO Molecular Medicine. 2009 Nov 1;1(8-9):371-380.
  3. Lambert JC, Schraen-Maschke S, Richard F, Fievet N, Rouaud O, Berr C, Dartigues JF, Tzourio C, Alpérovitch A, Buée L, Amouyel P. Association of plasma amyloid beta with risk of dementia: the prospective Three-City Study. Neurology. 2009 Sep 15;73(11):847-53. PubMed.

External Citations

  1. Leaflet
  2. details

Further Reading

No Available Further Reading