Antibody
p70 S6 Kinase phos Thr389 (108D2)
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Clonality: monoclonal
Host: Rabbit
Isotype: IgG
Source: Cell Signaling
Cat# 9234
Reference:
Zempel H, 2010
Formulation: liquid, HEPES, NaCl, BSA, glycerol
Reactivity:
Reacts in: Human, Mouse, Rat
Immunogen/Epitope
Immunogen = synthetic phospho-peptide corresp. to residues around Thr389 of human p70 S6 kinase
Specificity
detects endogenous levels of p70 S6 kinase only when phosphorylated at threonine 389; also detects p85 S6 kinase when phosphorylated at the analogous site (Thr412), and possibly S6KII phosphorylated at Thr401
References
Paper Citations
- Zempel H, Thies E, Mandelkow E, Mandelkow EM. Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci. 2010 Sep 8;30(36):11938-50. PubMed.
Further Reading
No Available Further Reading
Comments / Questions
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