Antibody

JNK1+2, phos T183/Y185

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Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Abcam
Cat# ab4821
Reference:
Zempel H, 2010
Formulation: liquid, affinity purified, glycerol, BSA, PBS, azide
Reactivity:
Reacts in: Human, Mouse
expect many others from homology

Immunogen/Epitope

immunogen = Synthetic peptide (Human) derived from the region of JNK 1 + 2 that contains threonine 183 and tyrosine 185, based on the human sequence (conservd among many species)

Specificity

detects JNK 1 + 2 phosphorylated at threonine 183 and tyrosine 185

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References

Paper Citations

  1. . Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci. 2010 Sep 8;30(36):11938-50. PubMed.

Further Reading

No Available Further Reading