Antibody

GFAP (GA5)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: Chemicon and Upstate are Millipore
cat# MAB360
References:
Burré J, 2010
Heneka, 2010
Van Uden, 2002, mono GFAP
Formulation: ascites, azide
Reactivity:
Reacts in: Bovine, Rabbit, Chicken, Pig, Human, Mouse, Rat

Immunogen/Epitope

purified GFAP from porcine spinal cord.

Specificity

recognizes ~50 kDa band; astrocytes and Bergmann glia cells, glioma and glial cell derived tumors

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References

Paper Citations

  1. Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC. Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science. 2010 Sep 24;329(5999):1663-7. PubMed.
  2. Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6058-63. PubMed.
  3. Van Uden E, Mallory M, Veinbergs I, Alford M, Rockenstein E, Masliah E. Increased extracellular amyloid deposition and neurodegeneration in human amyloid precursor protein transgenic mice deficient in receptor-associated protein. J Neurosci. 2002 Nov 1;22(21):9298-304. PubMed.

Further Reading

No Available Further Reading