Antibody

ERK phos Tyr204 (E-4)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG2a
Source: Santa Cruz
Cat# SC-7383
References:
Bosco DA, 2010
Zhang Y, 2010
Formulation: liquid, PBS, gelatin, azide, available conj. phycoerythrin sc-7838 PE, agarose sc-7838 AC, fluorescein sc-7383 FITC or rhodamine sc-7383 TRITC
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

Epitope corresponding to a sequence containing phosphorylated Tyr-204 of human ERK

Specificity

ERK1 and ERK2 phosphorylated at Tyr-204

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References

Paper Citations

  1. Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nat Neurosci. 2010 Nov;13(11):1396-403. PubMed.
  2. Zhang Y, Kurup P, Xu J, Carty N, Fernandez SM, Nygaard HB, Pittenger C, Greengard P, Strittmatter SM, Nairn AC, Lombroso PJ. Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19014-9. PubMed.

Further Reading

No Available Further Reading