The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

1806 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
14-3-3s From manufacturers (1)
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, azide, gelatin)
- Mammal (various), Cow, Human, Mouse, Rat immunogen = epitope mapping at the C-terminus of human 14-3-3β 14-3-3β and, to a lesser extent, other 14-3-3 family members -
ADAMS & ADAMTS From manufacturers (1)
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = apeptide mapping at the C-terminus of TACE of human origin for detection of precursor and mature TACE -
APP, APLP, AICD From labs (1)
(Konrad Beyreuther, Center of Molecular Biology, University of Heidelberg, Heidelberg, Germany)PaperReference: Kuhn, 2010 monoclonal
Mouse
- Human, Monkey, Mouse, Rat immunogen = a bacterial APP fusion protein (Fd-APP 695), (epitope in ectodomain, at residues 66-81 of APP) detects a variety of mature as well as immature APP species which differ in their degree of glycosylation -
APP, APLP, AICD From manufacturers (1)
MBL International polyclonal
IgG
Rabbit
(liquid, PBS, glycerol, BSA, azide, affinity purified)
- Frog, Human, Mouse, Rat immunogen = synthetic phosphopeptide, derived from the region of human APP that contains Thr688 (corresp. to the APP695 isoform) APP when phosphorylated at Thr668 -
ASK1/MAP3K5 From manufacturers (1)
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified)
- Human, Mouse, Rat Immunogen = peptide mapping at the N-terminus of human ASK1 ASK-1 -
ATPases From manufacturers (1)
Abcam monoclonal
IgG1
Mouse
(liquid, ascites, PBS, azide)
- Dog, Chicken, Human, Rat epitope = within an intracellular region at or near Asp-369 of the sodium/potassium ATPase alpha 1 subunit recognizes an epitope within an intracellular region at or near Asp-369 of the sodium/potassium ATPase alpha 1 subunit. -
Actin Related From manufacturers (1)
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, azide, gelatin, affinity purifiedAlso available as:sc-1616-R (rabbit)sc-1616 FITC sc-1616 PEsc-1616 TRICT sc-1616 B (biotin)sc-1616 HRPsc-1616 AC Cat# sc1616 AF405, AF488, AF647; Alexa Fluor®)
- Mammal (various), Dog, Zebra fish, Cow, Horse, Pig, Human, Mouse, Rat, Xenopus, C. elegans, S. cerevisiae, Drosophila immunogen = peptide mapping at the C-terminus of human actin broad range of Actin isoforms -
Akt and Serine/Threonine Kinases From manufacturers (4)
Alexis Enzo Life Sciences monoclonal
IgG1
Mouse
(lyophilized supernatant, azide, PEG, sucrose, purified)
- Dog, Human, Mouse, Rat Immunogen = synthetic peptide corresp. to C-terminal (PQFpSYSA) of human Akt (protein kinase B; PKB) phosphorylated at Ser473 Ser473-phosphorylated Akt; no cross-reaction with dephosphorylated Akt or unrelated serine-phosphorylated proteins. -
Alexis Enzo Life Sciences monoclonal
IgG1
Mouse
(lyophilized, PBS, azide, PEG, sucrose, purified)
- Dog, Human, Mouse, Rat Immunogen = synthetic peptide corresp. to C-terminal (QFpSYS A) of human Akt (protein Kinase B; PKB) dephosphorylated at Ser472/473/474 Akt dephosphorylated at Ser473; no cross-reaction with akt phosphorylated at Ser473 -
LifeSpan Biosciences, Inc. monoclonal
IgG1, κ
Mouse
(lyophilized, purified)
- Dog, Human, Mouse, Rat immunogen = synthetic peptide sequence (aa466-480) located at the C-terminus of Akt (KLH coupled) Akt1 -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide)
- Human, Mouse, Rat, Xenopus Immunogen = peptide mapping at the N-terminus of human Akt1 Akt1 and Akt2 -
Amyloid-β From labs (5)
WO2(Brian O'Nuallain,Graduate School of Medicine, University of Tennessee Medical Center, Knoxville, TN)PaperReference: Villemagne, 2010 monoclonal
IgM
Mouse
- Human, Mouse raised against sonicated amyloid fibrils grown from synthesized Aβ1–40 peptides (epitope at Aβ residues 5–8) detects amyloid-beta fibrils; exhibits Ab binding to fibrils in the presence of a large excess of Aβ(1–40) monomer, suggesting that Ab is directed against conformational epitopes that only exist in the fibril -
G2-11Konrad BeyreutherCenter for Molecular Biology Heidelberg (ZMBH), University of HeidelbergPaperReference: Villemagne, 2010 monoclonal
Mouse
(liquid, purified, PBS, BSAAlso see Chemicon MABN12)
- Human, Mouse immunogen = synthetic peptide corresponding to Aβ42, aa. 35-42 (MVGGVVIA), conjugated with KLH or BSA through a cysteine residue added at the N terminus of the peptides recognizes Amyloid β42 at the C-terminus -
G2-10Konrad BeyreutherCenter for Molecular Biology Heidelberg (ZMBH), University of HeidelbergPaperReference: Villemagne, 2010 monoclonal
Mouse
(liquid, purified, PBS, BSAAlso see Chemicon MABN11)
- Human, Mouse immunogen = synthetic peptide corresponding to Aβ40, aa. 33-40 (GLMVGGVV), conjugated with KLH or BSA through a cysteine residue added at the N terminus of the peptides recognizes Amyloid β40 at the C-terminus -
BAN-50(N Suzuki,Takada Chemical Industries)References:Wang S, 2010Fukumoto, 2010Suzuki, 1994 monoclonal
Mouse
- Human, Mouse raised against Aβ 1-16 (epitope at aa 1-10) amyloid-beta -
1E8(Paul Cutler,SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, Harlow, Essex, UKpaper: Cutler, et al, l997) monoclonal
Mouse
- Bovine, Human immunogen = the derived peptide sequence aa. 13–22, (epitope at aa. 18-22, VFFAE) of beta amyloid reacts with the N terminal of amyloid-beta; recognizes Aβ[1–40], Aβ[1–42] and Aβ[1–43] -
Amyloid-β From manufacturers (4)
Chemicon and Upstate are Millipore monoclonal
IgG2b
Mouse
(liquid, purified, buffer, Tris-glycine, BSA, azide)
- Human, Mouse immunogen = linear peptide of human Amyloid β40 at the C terminus recognizes Amyloid β40 at the C-terminus -
Innogenetics kit
Mouse
- Human Uses 21F12 as a capture antibody and incubation with biotinylated 3D6; 3D6 selectively binds Aß peptides with a free aminogroup at Asp1 (epitope 1–5) amyloid beta (cerebrospinal fluid) -
Genetics Company, Inc. monoclonal
IgG1
Mouse
(liquid, stabilizing solution, no azide, affinity purified, conj. HRP)
- Dog, Human, Guinea Pig, Mouse, Rat, Cynomolgus immunogen = Aβ 1-42 peptide at the C-terminus C-terminal of Aβ 1-42 peptide; not Aβ 1-38, Aβ 1-39, Aβ 1-40; low cross reactivity to Aβ 43 (10%)and Aβ 44 (13%) -
Cell Signaling polyclonal
Rabbit
(liquid, HEPES, NaCl, BSA, glycerol, affinity purified)
- Bovine, Human, Rat immunogen = synthetic peptide corresp. to residues at the N-terminus of human β-Amyloid peptides detects several isoforms of β-amyloid peptide (Abeta), such as Abeta-40, Abeta-42 etc, regardless of phosphorylation state -
Apolipoproteins From manufacturers (1)
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified, PBS, azide, blocking peptide)
- Mouse, Rat immunogen = a peptide mapping at the carboxy terminus of mouse ApoE Apo E -
CD147 From manufacturers (1)
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified, PBS, azide, gelatin)
- Mouse, Rat immunogen = peptide mapping at the C-terminus of EMMPRIN of mouse origin recognizes EMMPRIN, 55 kDa -
CD_ except CD11b, CD40, CD45 and CD147 From manufacturers (2)
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified IgG, PBS, azide, gelatinAlso available as rabbit IgG, sc-1505-R)
- Human, Mouse immunogen = peptide mapping at theC-terminus of PECAM-1 of human origin reacts with PECAM-1 -
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified IgG, PBS, azide, gelatinAlso available as rabbit IgG, sc-1506-RAvailable as agarose conjugate for IP, sc-1506 AC)
- Human, Mouse, Rat immunogen = peptide mapping at theC-terminus of PECAM-1 of mouse origin reacts with PECAM-1 -
Cell Death From manufacturers (13)
Novus Biologicals monoclonal
IgG1
Mouse
(liquid, PBS, azide, affinity purified)
- Human, Mouse immunogen = synthetic peptide corresp. to seq. in Ser155 region of mouse Bad and residue Ser155 is phosphorylated recognizes BAD only when phosphorylated at Ser 155 -
Novus Biologicals monoclonal
IgG1
Mouse
(liquid, PBS, azide, affinity purified)
- Human, Mouse immunogen = synthetic peptide corresp. to seq. in Ser155 region of mouse Bad and residue Ser155 is phosphorylated recognizes BAD only when phosphorylated at Ser 155 -
Novus Biologicals monoclonal
IgG1
Mouse
(liquid, azide, affinity purified)
- Mouse immunogen = synthetic phosphopeptide corresp. to residues surrounding Ser155 of mouse Bad, (conjugated with KLH) Bad - Bcl-associated death promoter (27AT381 ) [Ser155] -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified)
- Human, Mouse, Rat immunogen = peptide mapping at the N-terminus of human Bad Bad -
BioGenex polyclonal
IgG
Rabbit
(affinity purified, PBS, BSA, azide)
- Human immunogen = synthetic peptide encompassing a unique epitope at the N-terminus of human Bax protein coupled to KLH detects the α, β and δ isoforms of bax protein -
Biosource Invitrogen monoclonal
IgG1
Mouse
(liquid, ascites, PBS, azide, protein-A purified, unconj.)
- Human, Monkey immunogen = synthetic peptide corresp. to a sequence at the N-terminal of the human protein Bax -
Biosource Invitrogen monoclonal
IgG1, κ
Mouse
(liquid, ascites, PBS, BSA, azide, protein-A purified, unconj.)
- Human, Monkey immunogen = synthetic peptide corresp. to a sequence at the N-terminal of the human protein Bax -
Biosource Invitrogen monoclonal
IgG1
Mouse
(liquid, ascites, PBS, azide, protein-A purified, unconj.)
- Human, Rat immunogen = synthetic peptide corresp. to a sequence at the N-terminal of the human protein Bax -
Chemicon and Upstate are Millipore polyclonal
IgG1
Rabbit
(liquid, Tris-glycine, azide, protein A purified)
- Human immunogen = linear peptide corresp. to human BAX at and around the N-terminus, KLH conj. Bax -
LifeSpan Biosciences, Inc. monoclonal
IgG1
Mouse
(liquid, PBS, azide, protein A purified)
- Human, Monkey immunogen = synthetic peptide corresp. to a seq. at the N-terminal of human Bax Bax -
LifeSpan Biosciences, Inc. monoclonal
IgG1
Mouse
(liquid, BBS, azide, protein G purified)
- Human immunogen = peptide corresp. to aa 3-16 at the N- terminus of human Bax, KLH-conjugated Bax -
LifeSpan Biosciences, Inc. monoclonal
IgG1
Mouse
(liquid, BBS, azide, protein G purified)
- Human, Mouse, Rat immunogen = peptide corresp. to aa 12-24 at the N- terminus of human Bax, KLH-conjugated Bax -
LifeSpan Biosciences, Inc. monoclonal
IgG1
Mouse
(liquid, PBS, azide, protein A purified)
- Human, Mouse, Rat immunogen = synthetic peptide corresp. to a sequence at the N-terminal of the protein which is common to human, mouse and rat Bax -
Cytokines & Receptors From manufacturers (1)
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, azide, gelatin, affinity purified)
- Human, Mouse, Rat immunogen = a peptide mapping at the N-terminus of TNFα of mouse origin reacts with TNFα -
Cytoskelatal Proteins From manufacturers (2)
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, azide, gelatin, affinity purified)
- Cow, Pig, Human, Mouse, Rat immunogen = peptide mapping at the C-terminus of human cofilin recognizes Cofilin 1 and Cofilin 2 -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, azide, gelatin, affinity purified)
- Cow, Pig, Human, Mouse, Rat immunogen = peptide mapping at the N-terminus of human cofilin 1 recognizes Cofilin 1 and Cofilin 2 -
Gap Junctions From manufacturers (3)
Santa Cruz polyclonal
Goat
(affinity purified, liquid, PBS, azide, gelatinAlso available as rabbit rabbit, sc-7261-R)
- Human, Mouse, Rat immunogen = a peptide mapping at the N-terminus of connexin 26 of human origin polyclonal for detection of connexin 26, and toa lesser extent, connexin 30 -
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified IgG, PBS, azide, gelatin.Also available sc-6560 AC, agarose conj.)
- Dog, Zebra fish, Cow, Human, Mouse, Rat, Xenopus immunogen = a peptide mapping at the C-terminus of connexin 43 of human origin recommended for detection of connexin 43. -
Santa Cruz polyclonal
IgG
Rabbit
(liquid IgG, PBS, azide, gelatin)
- Zebra fish, Human, Mouse, Rat, Xenopus immunogen = aminoacids 233-382 mapping at the C-terminus of connexin 43 of human origin recommended for detection of connexin 43. -
Glutamate Receptor & Related From manufacturers (3)
Sigma Aldrich polyclonal
Rabbit
(lyophilized, NH4HCO3, affinity purified)
- Human, Mouse, Rat Immunogen = amino acids 984-1104 at C-terminus of NR2B NMDAR2B (180kDa). No cross-reaction with NR2A aor NR2C subunits -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(lyophilized from PBS, BSA, azide, affinity purified)
- Equine, Human, Mouse, Rat Immunogen = KLH-conjugated linear peptide corresponding to human Glutamate receptor 1 at the cytoplasmic domain detects GluR1, cytoplasmic domain -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(liquid, unpurified serum, azide)
- Mouse, Rat immunogen = GST-tagged recombinant protein corresponding to rat NR2A at the C-terminus recognizes NR2A (~176 kDa) at the C-terminus -
Histones & HDACs From manufacturers (2)
Upstate and Chemicon are Millipore polyclonal
IgG
Rabbit
(liquid, rabbit serum, azide)
- Mammal (various), Human, Mouse immunogen = a KLH-conjugated, branched synthetic peptide containing the sequence ..Rme2KSTG.., in which me2K corresponds to dimethyl-lysine at residue 9 of human histone H3 specific for Dimethyl-Histone H3 (Lys9) -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, azide, gelatin)
- Human immunogen = epitope corresp. to aa 916-1215 mapping at the C-terminus of HDAC6 of human origin detects HDAC6, 160 kDa -
Interleukins From manufacturers (1)
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, azide, gelatin, affinity purified)
- Mouse, Rat immunogen = a peptide mapping at the C-terminus of IL-6 of mouse origin reacts with IL-6, 21-28 kDa by WB -
Kinases From manufacturers (4)
Santa Cruz polyclonal
IgG
Rabbit
(liquid, affinity purified IgG, PBS, azide, gelatinAvailable as agarose (sc-562 AC) conjugate for IP)
- Bovine, Human, Mouse, Rat immunogen = a peptide mapping at the C-terminus of GRK 2 of human origin for detection of GRK2 -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, affinity purified IgG, PBS, azide, gelatin)
- Cow, Human, Mouse, Rat immunogen = a peptide mapping at the C-terminus of GRK 3 of bovine origin for detection of GRK3 -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, affinity purified IgG, PBS, azide, gelatinAvailable as agarose conjugate for IP, sc-566 AC,)
- Bovine, Human, Mouse, Rat immunogen = a peptide mapping at the C-terminus of GRK 6 of human origin for detection of GRK6 -
Santa Cruz polyclonal
IgG1
Goat
(liquid, PBS, azide, gelatin, affinity purified Also available as agarose conj. for IP, Cat# sc-6481 AC)
- Bovine, Human, Mouse, Rat immunogen = epitope mapping at the C-terminus of human Casein Kinase IIα ' detects Casein Kinase IIα' -
MAPKs From manufacturers (2)
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, gelatin, azide, affinity purified,Also available conjugated to PE, sc-93PE, or to agarose, sc-93AC)
- Chicken, Frog, Human, Mouse, Rat Immunogen = peptide mapping at the C-terminus of rat ERK1 recognizes ERK1 p44 and, to a lesser extent, ERK2 p42 -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, gelatin, azide, afffinity purified)
- Chicken, Zebra fish, Human, Mouse, Rat, Xenopus Immunogen = peptide mapping at the C-terminus of rat ERK 2 detects ERK 2 p42, and to a lesser extent, ERK 1 p44 -
MAPs From manufacturers (1)
nanoTools Antikörpertechnik GmbH & Co. monoclonal
IgG1
Mouse
(liquid)
- Human, Monkey, Hamster, Mouse, Rat immunogen = synthetic peptide conjugated to hemocyanin (epitope at N-Terminus of LC3-B) recognizes MAP1 light chain component LC-3 -
Motor Proteins From manufacturers (1)
Chemicon and Upstate are Millipore monoclonal
IgG2b
Mouse
(liquid, phosphate buffer, saline, azide)
- Mammal (various), Chicken, Sea Urchin, Squid, Human, Mouse, Rat, Clam immunogen = bovine brain kinesin, epitope at aa 420-445 Reacts with the heavy chain of kinesin near the N-terminus -
Neural Progenitors From manufacturers (2)
Santa Cruz polyclonal
IgG
Goat
(liquid IgG, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = peptide mapping at the C-terminus of Doublecortin of human origin recognizes doublecortin -
Santa Cruz polyclonal
IgG
Goat
(liquid IgG, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = peptide mapping at the N-terminus of Doublecortin of human origin 40 kDa doublecortin -
Nitric Oxide From manufacturers (1)
BD Transduction monoclonal
IgG1
Mouse
(aqueous buffered solution containing BSA, glycerol, azide)
- Mouse immunogen = mouse iNOS aa. 961-1144 at C-terminal recognizes ~130 kDa iNOS; reported to cross-react with nNOS and eNOS -
Phosphatases From manufacturers (1)
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
- Mouse, Rat immunogen = an 18 amino acid sequence mapping at the N-terminus of STEP46 of rat origin for detection of all known isoforms of STEP of mouse and rat origin -
Posttranslational Modifications From labs (1)
Ubi-B1 and Ubi-B2(Fred W. van Leeuwen, Netherlands Institute forBrain Research, Amsterdam, Netherlands)Paper polyclonal
Rabbit
(See also R&D systems antibodies MAB703 andAF703)
- Human immunogen = synthetic peptides covering YADLRED PDRQDHH PGSGAQ at the C-terminus of Ubiquitin+1 reacts with Ubiquitin+1 and not Ubiquitin -
Proteases From manufacturers (4)
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified)
- Human, Mouse, Rat immunogen = peptide mapping at the C-terminus of human cathepsin B cathepsin B -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified; sc-6493P blocking peptide)
- Human, Mouse, Rat immunogen = peptide mapping at the N-terminus of human cathepsin B cathepsin B -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified; sc-6491P blocking peptide)
- Human immunogen = peptide mapping at the N-terminus of human cathepsin B cathepsin B -
Cell Technology kit
Unknown Host
(substrate-based assay, cell permeable, fluorogenic, lyophilized)
- - - - -
Protein Trafficking From manufacturers (1)
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, azide, gelatin, affinity purifiedAlso available as agarose conjugate for IP studies, sc-1924 AC)
- Dog, Human, Mouse, Rat immunogen = mapping at the C-terminus of Annexin II of human origin detects Annexin II and, to a lesser extent, Annexin I, III, IV, V, VI and XI -
Protein Translation From manufacturers (1)
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = apeptide mapping at the N-terminus of eIF3η of human origin detects eIF3η -
Secreted Neuropeptides & Receptors From manufacturers (2)
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified IgG, PBS, azide, gelatin)
- Dog, Pig, Human, Mouse, Rat immunogen = a peptide mapping at the C-terminus of Orexin-A of human origin for detection of Orexin-A processed active peptide -
Santa Cruz polyclonal
IgG
Goat
(affinity purified, PBS, azide, gelatin)
- Cow, Human, Mouse, Rat immnuogen = a peptide mapping at the C-terminus of urocortin of rat origin detects urocortin -
Synucleins From labs (1)
α-Synuclein LB509(Takeshi Iwatsubo, Department of Neuropathology & Neuroscience, Grad. School of Pharmaceutical Sciences, University of Tokyo)Also see Abcam ab27766, SantaCruz sc-58480, and others.References:Tokuda, 2010Tsika, 2010Xu, 2002 monoclonal
Mouse
- Human (epitope at the C terminus of the protein, residues 115-122) detects α-Synuclein, C-terminal -
Synucleins From manufacturers (1)
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, gelatin, azide, affinity purified)
- Human, Mouse, Rat immunogen = aa mapping at C-terminus of human α-synuclein ~19 kDa α-synuclein -
TAR DNA-binding protein /TDP-43 From manufacturers (1)
Abnova Corporation monoclonal
IgG1
Mouse
(liquid, PBS)
- Human immunogen = TARDBP (AAH01487, aa 1 ~261) full length recombinant protein with GST tag. (epitope at aa 205-222) recognizes aa 205–222 of human TDP-43, correspond. to a part of the second RNA recognition motif (RRM2);also recognizes 25 kDa C-terminal fragments -
Tau From labs (5)
TauC3(Vincent L. Cryns, Cell Death Regulation Laboratory, Division of Endocrinology,Metabolism, and Molecular Medicine, Northwestern University, Chicago, IL)Research paperReference: Alonso, 2010 monoclonal
IgG1
Mouse
(purified IgG, HEPES, saline, glycerol.)
- Human immunogen = KLH- C S S T G S I D M V D, corresp. to residues 412-421 at the C-terminus of tau truncated at Asp421 recognizes tau when truncated at Asp421; no reaction with full-length tau, or with tau truncated at Glu391 or Ala429 -
Ab708Li Gan, Gladstone Institute of Neurological DiseaseAssistant Professor of NeurologyUniversity of California, San FranciscoReference: Min SW, 2010 polyclonal
IgG2b
Rabbit
- Human, Rat immunogen = a synthetic tau peptide (amino acids 160–182 for 2N4R tau isoform) containing acetylated lysines at positions 163 and 174 and 180 Ab708 specifically recognizes tau acetylated by p300 under cell-free conditions. In HEK293T cells transfected with tau, overexpression of p300 markedly elevatedthe levels of ac-tau detected with Ab708 while the increase in the levels of t-tau was modest, suggesting that Ab708 preferentially recognizes p300-induced ac-tau in cultured cells. Ab708 recognizes human tau acetylated at positions 163, 174, or 180 and possibly other acetylated lysines on tau, but not nonacetylated tau -
Philip Dolan, Prothena Biosciences, South San Francisco, CA monoclonal
Mouse
- Mammal (various), Human, Zebra fish, Drosophila, C. elegans immunogen = tau phosphorylated at S262 in KXGS motif of the 4th repeat and/or Ser356 tau phosphorylated at S262 and/or S356 -
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
IgG1
Mouse
- Human, Mouse epitope at aa102–140 recognizes total tau -
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
IgM
Mouse
(IC, IF, IH, IP, WB)
- Human Tau phosphorylated at threonine-231; also conformation-sensitive. Tau phosphorylated at threonine-231; also conformation-sensitive. Not reactive to normal tau. The TG3 epitope is expressed in mitotic cells but not in quiescent cells, suggesting that mitotic phosphoepitopes may lead to conformational changes. -
Tau From manufacturers (18)
- monoclonal
IgG1κ
Mouse
(liquid, PBS, sterile filtered, affinity purified)
- Human partially purified human tau, aa. around phosphorylated Serine 202 Recognizes phosphorylated paired helical filament tau. Recognises tau protein phosphorylated at both serine 202 and threonine 205. No cross-reactivity with unphoshorylated tau. -
Innogenetics kit
Unknown Host
(solid-phase ELISA, uses monoclonal HT7 for capture, AT270 biotinylated for incubation, streptavidin; working range: 25 to 150 pg/mL)
- Human   specific for tau phosphorylated at threonine 181, antigen in cerebrospinal fluid (CSF) -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human tau-derived peptide that is phospho. at serines 199 and 202 tau phosphorylated at serines 199 and 202 -
Biosource Invitrogen polyclonal
Rabbit
(affinity purified Ig)
- Human immunogen = human tau-derived synthetic peptide that is phosphorylated at serine 202 tau phosphorylated at serine 202 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol)
- Human human tau-derived peptide that is phosphorylated at serine 262 tau phosphorylated at serine 262 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at serine 409 tau phosphorylated at serine 409 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at threonine 212 tau, tau phosphor. at threonine 212 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at threonine 217 tau phosphorylated at threonine 217 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at threonine 231 tau phosphorylated at threonine 231 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at serine 404 tau phosphorylated at serine 404 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at serine 400 tau phosphorylated at serine 400 -
Biosource Invitrogen monoclonal
IgG1
Mouse
(affinity purified ascites, PBS, BSA, azide, unconj.)
- Human, Mouse, Rat immunogen = KLH- CSSTGSIDMVD, corresp. to the C-terminus of tau truncated at Asp421 recognizes tau when truncated at Asp421; no reaction with full-length tau, or with tau truncated at Glu391 or Ala429 -
Biosource Invitrogen kit
Unknown Host
(contains:Hu Tau [pT181]Antibody Bead Concentrate;Hu Tau [pT181]Detection Ab Concentrate;Hu Tau [pT181] Standard)
- Human human tau-derived peptide that is phosphorylated at threonine 181 for the measurement of human Tau when phosphorylated at threonine 181 in CSF and tissueculture media -
Chemicon and Upstate are Millipore monoclonal
IgG2a
Mouse
(purified Ig, phosphate buffered, lyophilized)
- Bovine, Human, Rat immunogen = purified denaturated bovine MAPs (epitope at or near a phosphorylated site) binds to all known electrophoretic species of tau in human, rat and bovine brain (one-dimensional SDS-PAGE); there is some unphosphorylated bias with clone PC1C6 as it seem to recognize only dephosphorylated serine sites at 195, 198, 199, and 202 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at threonine 205 tau phosphorylated at threonine 205 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at serine 422 tau phosphorylated at serine 422 -
Pierce Thermo Scientific monoclonal
IgG1κ
Mouse
(supernatant, affinity purified, no carrier or preservativeAlso available biotin conj., MN-1050B)
- Human immunogen == partially purified human PHF tau, aa. around phosphorylated Thr181 PHF tau, tamgles and neurofilaments; no cross with recomb. unphospho tau; weak cross with normal tau -
Pierce Thermo Scientific monoclonal
IgG1κ
Mouse
(purified, no carrier or preservative)
- Human immunogen = aa. around phosphorylated Thr231 detects Tau doubly phosphorylated at Thr231 and Ser235; weak recognition of phosphorylation at Thr231 only -
Transcription Factors From manufacturers (2)
Santa Cruz polyclonal
IgG
Goat
(IgG, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = a peptide mapping at the N-terminus of TIAR of human origin recognizes TIAR and, to a lesser extent,TIA-1 -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified)
- Human, Mouse, Rat Immunogen = peptide mapping at the N-terminus of Neuro D of mouse origin Neuro D -
Tubulin From manufacturers (1)
Sigma Aldrich monoclonal
IgG1
Mouse
(liquid, purified IgG, PBS, BSA, azideAlso available as ascites and as FITC conj.)
- Bovine, Chicken, Human, Mouse immunogen = purified chick brain tubulin (epitope at aa 426-430) recognizes an epitope located at the C-terminal end of alpha-tubulin -
γ-secretase/ Presenilins From manufacturers (1)
A D I polyclonal
Goat
(unpurified antiserum)
- Human immunogen = a 20-aa peptide from human Presenilin-1, at the N-terminus, extracellular region Presenilin-1; no cross with PS2 or other known proteins -