Antibody

Aβ 42 (G2-13)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1,κ
Source: Genetics Company, Inc.
Cat# CP13
References:
Lefterov, 2010
Fitz, NF, 2010
Formulation: liquid, stabilizing solution, no azide, affinity purified, conj. HRP
Reactivity:
Reacts in: Dog, Human, Guinea Pig, Mouse, Rat, Cynomolgus

Immunogen/Epitope

immunogen = Aβ 1-42 peptide at the C-terminus

Specificity

C-terminal of Aβ 1-42 peptide; not Aβ 1-38, Aβ 1-39, Aβ 1-40; low cross reactivity to Aβ 43 (10%)and Aβ 44 (13%)

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References

Paper Citations

  1. Lefterov I, Fitz NF, Cronican AA, Fogg A, Lefterov P, Kodali R, Wetzel R, Koldamova R. Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice. J Biol Chem. 2010 Nov 19;285(47):36945-57. Epub 2010 Aug 25 PubMed.
  2. Fitz NF, Cronican A, Pham T, Fogg A, Fauq AH, Chapman R, Lefterov I, Koldamova R. Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice. J Neurosci. 2010 May 19;30(20):6862-72. PubMed.

Further Reading

No Available Further Reading