Antibody

Tau pS262

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Clonality: polyclonal
Host: Rabbit
Source: Biosource Invitrogen
Cat# 44-750G
References:
Kosmidis, 2010
Planel, 2008
Yuzawa, 2008
Shahani, 2006
Formulation: purified Ig, PBS, BSA, azide, glycerol
Reactivity:
Reacts in: Human
expect mouse, rat, cow, goat, baboon and monkey

Immunogen/Epitope

human tau-derived peptide that is phosphorylated at serine 262

Specificity

tau phosphorylated at serine 262

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References

Paper Citations

  1. Kosmidis S, Grammenoudi S, Papanikolopoulou K, Skoulakis EM. Differential effects of Tau on the integrity and function of neurons essential for learning in Drosophila. J Neurosci. 2010 Jan 13;30(2):464-77. PubMed.
  2. Planel E, Krishnamurthy P, Miyasaka T, Liu L, Herman M, Kumar A, Bretteville A, Figueroa HY, Yu WH, Whittington RA, Davies P, Takashima A, Nixon RA, Duff KE. Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo. J Neurosci. 2008 Nov 26;28(48):12798-807. PubMed.
  3. Yuzwa SA, Macauley MS, Heinonen JE, Shan X, Dennis RJ, He Y, Whitworth GE, Stubbs KA, McEachern EJ, Davies GJ, Vocadlo DJ. A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo. Nat Chem Biol. 2008 Aug;4(8):483-90. PubMed.
  4. Shahani N, Subramaniam S, Wolf T, Tackenberg C, Brandt R. Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau constructs in organotypic hippocampal slices. J Neurosci. 2006 May 31;26(22):6103-14. PubMed.

Further Reading

No Available Further Reading