Antibody
α-Synuclein (C-20)
Quick Links
Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Santa Cruz
Cat# sc7011-R
References:
Emmanouilidou, 2010
Ihara, 2007
Formulation: liquid, PBS, gelatin, azide, affinity purified
Reactivity:
Reacts in: Human, Mouse, Rat
Immunogen/Epitope
immunogen = aa mapping at C-terminus of human α-synuclein
Specificity
~19 kDa α-synuclein
References
Paper Citations
- Emmanouilidou E, Melachroinou K, Roumeliotis T, Garbis SD, Ntzouni M, Margaritis LH, Stefanis L, Vekrellis K. Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival. J Neurosci. 2010 May 19;30(20):6838-51. PubMed.
- Ihara M, Yamasaki N, Hagiwara A, Tanigaki A, Kitano A, Hikawa R, Tomimoto H, Noda M, Takanashi M, Mori H, Hattori N, Miyakawa T, Kinoshita M. Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity. Neuron. 2007 Feb 15;53(4):519-33. PubMed.
Further Reading
News
- Microglia in ALS: Helpful, Harmful, or Neutral?
- Turning Rett Syndrome Protein From Repressor Into Activator
- Glia—Absolving Neurons of Motor Neuron Disease
- Rett Symptoms Reversed in Mice
- Multitasking Rett Protein Shines Spotlight on RNA Splicing in Neurologic and Psychiatric Disease
- Rett-icent Neurological Disorder Reveals Some Secrets
Comments / Questions
No Available Comments
Make a comment or submit a question
To make a comment you must login or register.