Antibody

Apo E (M-20)

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Clonality: polyclonal
Host: Goat
Isotype: IgG
Source: Santa Cruz
Cat# sc-6384
References:
Reference:
Lefterov, 2010
Fitz, NF, 2010
Wahrle, 2008
Sagare, 2007
Formulation: liquid, affinity purified, PBS, azide, blocking peptide
Reactivity:
Reacts in: Mouse, Rat

Immunogen/Epitope

immunogen = a peptide mapping at the carboxy terminus of mouse ApoE

Specificity

Apo E

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References

Paper Citations

  1. Lefterov I, Fitz NF, Cronican AA, Fogg A, Lefterov P, Kodali R, Wetzel R, Koldamova R. Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice. J Biol Chem. 2010 Nov 19;285(47):36945-57. Epub 2010 Aug 25 PubMed.
  2. Fitz NF, Cronican A, Pham T, Fogg A, Fauq AH, Chapman R, Lefterov I, Koldamova R. Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice. J Neurosci. 2010 May 19;30(20):6862-72. PubMed.
  3. Wahrle SE, Jiang H, Parsadanian M, Kim J, Li A, Knoten A, Jain S, Hirsch-Reinshagen V, Wellington CL, Bales KR, Paul SM, Holtzman DM. Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. J Clin Invest. 2008 Feb;118(2):671-82. PubMed.
  4. Sagare A, Deane R, Bell RD, Johnson B, Hamm K, Pendu R, Marky A, Lenting PJ, Wu Z, Zarcone T, Goate A, Mayo K, Perlmutter D, Coma M, Zhong Z, Zlokovic BV. Clearance of amyloid-beta by circulating lipoprotein receptors. Nat Med. 2007 Sep;13(9):1029-31. PubMed.

Further Reading

No Available Further Reading