Is Brain Training More Than Just Fun and Games?
Brain-training websites tout their games’ potential to boost cognition, but strong evidence and firm backing by the scientific community have yet to surface.
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DREAM Challenge Tackles Alzheimer’s Biomarkers
Big-data project takes on Alzheimer's with a biomarker computational challenge.
More Accurate Ways to Measure CSF Aβ Debut
A candidate reference method for measuring Aβ42 in cerebrospinal fluid brings researchers closer to standardization.
Blood Patterns: Prowling for Alzheimer’s Clues in Plasma
Will an antibody signature make for a new Alzheimer’s diagnostic?
Three’s Company: Florbetaben Approved, Excludes AD Diagnosis
European and U.S. agencies approve a third amyloid PET tracer, florbetaben.
Do Frontoparietal Regions Shrink First in Preclinical Alzheimer’s?
A small longitudinal study suggests that atrophy begins in the frontoparietal cortex, not the hippocampus, in early Alzheimer's.
Fluid Markers and Imaging Back Idea of Breached Blood-Brain Barrier
Do blood components really leak across an inflamed blood-brain barrier early on in the development of Alzheimer’s disease? Some GWAS hits and budding neuro-imaging and fluid markers are helping researchers find out.
Prodromal Initiative to Identify Biomarkers for Parkinson’s
Keystone symposium highlights new strategies in the quest to find the biomarkers of Parkinson’s disease.
Test Uses 'Seeding' to Detect Aβ Oligomers in Cerebrospinal Fluid
A new test claims to detect Aβ oligomers in cerebrospinal fluid by exploiting their tendency to seed aggregation.
For Hockey Players, Brain Damage Can Be Measured in Blood
Researchers have found protein traces of brain damage in the blood of hockey players who sustained a concussion. Could biomarkers help decide when athletes return to their sport?
Amyvid Follows in PiB’s Footsteps
The amyloid imaging agent florbetapir predicts cognitive decline much like its forerunner, PiB.
Do Lipids Hold the Key to Blood-Based Alzheimer’s Test?
Low levels of 10 phospholipids in blood plasma correlated with future cognitive decline in older adults, hinting at diagnostic potential.
DIAN Longitudinal Data Surprises With Late Drop in Tau
The first longitudinal data from DIAN conflict with some cross-sectional findings, revealing a small drop in CSF injury markers after the first appearance of symptoms of disease.
Test Closes in on Oligomers, May Distinguish Alzheimer’s Patients From Controls
Detecting oligomers in the cerebrospinal fluid is no easy feat. The latest test is among the most sensitive yet, but is it useful?
New Initiative AMPs Up Alzheimer’s Research
Government, industry, and advocacy together will provide nearly $130 million for the identification of surrogate markers and targets.
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