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By amplifying small quantities of Aβ oligomer in cerebrospinal fluid, a methodology referred to as the "bio-barcode" could serve as a diagnostic or monitoring test for AD...
Finding an easily measurable antecedent marker for Alzheimer disease would be a major development. Might glycogen synthase kinase fit the bill?...
Surveying the protein profile of a tissue or body fluid by traditional methods has not proven a very efficient way to detect changes in protein levels in neurodegenerative diseases...
The chemokine receptor CCR1 might be an early and specific marker of Alzheimer's disease, researchers suggest in the November issue of Annals of Neurology, now available online...
The ratio of phosphorylated tau (p-tau) to β-amyloid (Aβ) in the cerebrospinal fluid improves the ability to distinguish clinically defined Alzheimer's patients from normal subjects, according to a study...
Could biopsy of olfactory epithelium yield early warnings of Alzheimer's disease (AD)? This possibility was raised by George Perry and colleagues who report that oxidative damage to olfactory neurons could be a harbinger of impending AD...
Soon after the World Health Organization bestowed its approval on the protein 14-3-3 as an important diagnostic marker for sporadic Creutzfeldt-Jakob disease (sCJD), reports began to come in that its sensitivity and specificity might not be all that was advertised...
Assays of Aβ or tau protein in cerebrospinal fluid can identify Alzheimer's disease in patients with mild cognitive impairment, say the authors of a study in today’s Archives of Neurology...
Today at the annual meeting of the Society for Neuroscience, <strong>Lee Goldstein</strong> of Massachusetts General Hospital presented evidence suggesting that the Aβ peptide occurs in the eyes of people with Alzheimer’s disease...
Humans who live longer display the same biomarkers found in laboratory animals who have restricted caloric intake. However, because these human subjects weren't actively restricting their caloric intake, there may be other ways to increase life span in humans...
One of the most coveted achievements AD researchers are striving for these days is to develop a biomarker that could, simply and inexpensively, detect if a person has early Alzheimer's disease...
