Studies Suggest Mitochondria Changes Precede Aging, Alzheimer’s
Studies support the idea that mitochondrial changes drive aging and AD pathogenesis.
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Biomarkers Predict Alzheimer’s, But Shoe Does Not Always Fit
Studies reported at AAIC demonstrate that biomarkers help predict who will develop cognitive impairment and dementia.
Suspected Non-Amyloid Pathology (SNAP)—Not an Open or Shut Case
AD but no Amyloidβ? Researchers at AAIC 2013 theorized on the pathology underlying this form of dementia.
In Familial AD, Aβ Production Up, Clearance Down
Researchers have long assumed that people with familial Alzheimer’s disease make too much Aβ42 in the brain, but they lacked proof.
Do Biomarkers Improve Diagnostic Accuracy?
It’s a scenario familiar to many clinicians: A patient diagnosed with mild cognitive impairment asks if he or she will eventually develop Alzheimer’s disease.
Study Finds Ways to Predict, Track Huntington’s Disease
Anticipating future clinical trials for Huntington’s disease, researchers are seeking sensitive measures that will predict onset and track progression...
Not Seeing Eye to Eye: Do Lenses Accumulate Aβ?
What if you could diagnose Alzheimer’s disease at an early stage by examining a person’s eyes?...
Longitudinal Data Stand Out at AD/PD Imaging Satellite
The 11th AD/PD Conference hosted a day-long exchange of new imaging data and discussion of current challenges for the research community in these two disorders...
From Natural History, A "Renaissance" for Amyloid Hypothesis
Scientists quipped about Florence as a fitting setting for what they perceive to be a resurgence of the amyloid hypothesis after a beleaguered period of setbacks...
Wrapping Up Enrollment, ADNI 2, PPMI Focus on Earlier Disease
The Alzheimer’s Disease Neuroimaging Initiative steering committee gathered to exchange the latest developments in ADNI 2...
FDA Invites Comment on Drug Testing Guidance for Early AD
Scientists have turned their attention toward testing therapies in early-stage patients who have underlying brain pathology but little to no functional impairment...
Dementia in Movement Disorders: What Causes It?
Adding insult to injury, many patients with a movement disorder get dementia, too...
Aβ*56 Found in Human CSF, Correlates With Tau?
Growing evidence suggests that neurons begin faltering decades before cognitive symptoms in AD, but identifying the molecular culprits at play has proven challenging...
More Bang for the Buck? DESCRIPA Thrifty in Biomarker Studies
Among global initiatives aimed at understanding how biomarkers elucidate the progression of Alzheimer’s disease, DESCRIPA appears to do much with little...
HAI—Aβ: First in Alzheimer’s Cascade, or Just Another Player?
Scientists worldwide now perform amyloid imaging on scores of research participants to figure out how Aβ buildup relates to other markers of neurodegeneration...
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