Creutzfeldt-Jakob Disease (Sporadic) vs Alzheimer's Disease: tau-total (CSF)

BIOMARKER META ANALYSIS 11.6844238985279 9.169586997710841 14.8889761201428 19.8795457697464 6.11852402964487E-88 0.847322239820066 0.126674702178911 Biomarker Comparison Reference:  Biom Comparison: 1695091_1695081 Effect Metric:  5.42106808787549 Lower CI:  3.30752052842167 Up

Creutzfeldt-Jakob Disease (Sporadic) vs Alzheimer's Disease: tau-total (Plasma and Serum)

BIOMARKER META ANALYSIS 5.59904622720101 1.06071173374021 29.5549843158537 2.02940173008638 0.0424173890471998 0.930447884154444 1.34479937159494 Biomarker Comparison Reference:  Biom Comparison: 1705801_1705796 Effect Metric:  2.28798506693392 Lower CI:  1.00340889620157 Upper

Alzheimer's Disease vs Control: α-synuclein (CSF)

BIOMARKER META ANALYSIS 1.18317540464243 1.07834187179433 1.29820057513058 3.55334335571479 0.000380367650559261 0.90718193124733 0.0402798772807433 Biomarker Comparison Reference:  Biom Comparison: 1700781_1700766 Effect Metric:  0.796501203994091 Lower CI:  0.701678933835322 U

Alzheimer's Disease vs Control: α-synuclein (Plasma and Serum)

BIOMARKER META ANALYSIS 0.909152968936571 0.75188861816564 1.09931059063338-0.98286462941928 0.325674068110837 Biomarker Comparison Reference:  Biom Comparison: 1701006_1701001 Effect Metric:  0.864210608972445 Lower CI:  0.67653156194867 Upper CI:  1.10395437355396 LN Effect Me

CBS vs Alzheimer's Disease: α-synuclein (CSF)

BIOMARKER META ANALYSIS 0.735892578279753 0.61696408414675 0.877746210326262-3.40984262790331 0.0006500037458177799 Biomarker Comparison Reference:  Biom Comparison: 1697501_1697496 Effect Metric:  0.693095653265163 Lower CI:  0.528500798529625 Upper CI:  0.908951482971384 LN Ef

Control vs Alzheimer's Disease: α-synuclein (CSF)

BIOMARKER META ANALYSIS 0.845183221419489 0.770296993513051 0.927349689515465-3.55334335571479 0.000380367650559261 0.90718193124733 0.0402798772807433 Biomarker Comparison Reference:  Biom Comparison: 1700766_1700781 Effect Metric:  1.2554908831091 Lower CI:  1.10602658210984 U

Control vs Alzheimer's Disease: α-synuclein (Plasma and Serum)

BIOMARKER META ANALYSIS 1.09992491271264 0.909661026210839 1.32998422351394 0.98286462941928 0.325674068110837 Biomarker Comparison Reference:  Biom Comparison: 1701001_1701006 Effect Metric:  1.15712534608781 Lower CI:  0.905834538053147 Upper CI:  1.47812763844989 LN Effect Me

Dementia with Lewy Bodies vs Alzheimer's Disease: α-synuclein (CSF)

BIOMARKER META ANALYSIS 0.821624729570073 0.7302683876363401 0.92440972068651-3.26691914526732 0.00108724727929635 0.8152774899194219 0.0444238115802313 Biomarker Comparison Reference:  Biom Comparison: 1700776_1700781 Effect Metric:  0.984228751771658 Lower CI:  0.7819504475055

Frontotemporal Dementia vs Alzheimer's Disease: α-synuclein (CSF)

BIOMARKER META ANALYSIS 0.864013366176466 0.583499725500402 1.27938208761175-0.729808496784015 0.465507250047436 0.759447076813464 0.111618450239752 Biomarker Comparison Reference:  Biom Comparison: 1700836_1700831 Effect Metric:  1.3269880972113 Lower CI:  0.96990802787016 Uppe

MCI-AD vs MCI-Stable: α-synuclein (CSF)

BIOMARKER META ANALYSIS 1.34025893795542 0.990255537464086 1.81397018528114 1.89655035166406 0.0578873085315796 0.36402090743491 0.0262587020502808 Biomarker Comparison Reference:  Biom Comparison: 1701761_1701756 Effect Metric:  1.18147798589823 Lower CI:  0.825300412712638 Upp

Multiple System Atrophy vs Alzheimer's Disease: α-synuclein (CSF)

BIOMARKER META ANALYSIS 0.594082219112101 0.539000819473563 0.65479247955479-10.4894161745358 9.66235738875016E-26 0.18192562198113 0.00229811224313395 Biomarker Comparison Reference:  Biom Comparison: 1700956_1700941 Effect Metric:  0.670298074601471 Lower CI:  0.47165825703564

Parkinson's Disease Dementia vs Alzheimer's Disease: α-synuclein (CSF)

BIOMARKER META ANALYSIS 0.665551864466371 0.597318073842771 0.741580246257977-7.37728343076779 1.61551854369019E-13 0.388833529607636 0.00584828757593017 Biomarker Comparison Reference:  Biom Comparison: 1697526_1697496 Effect Metric:  0.61389244615362 Lower CI:  0.5212615362808

Parkinson's Disease vs Alzheimer's Disease: α-synuclein (CSF)

BIOMARKER META ANALYSIS 0.757502038709004 0.670915117388332 0.855263689514052-4.48445201414176 7.31015539509934E-6 0.836607372767001 0.0371251650594997 Biomarker Comparison Reference:  Biom Comparison: 1700771_1700781 Effect Metric:  1.21448656866055 Lower CI:  0.956289757720367

Progressive Supranuclear Palsy vs Alzheimer's Disease: α-synuclein (CSF)

BIOMARKER META ANALYSIS 0.6932966980602649 0.630580860279948 0.762250080549345-7.5717651157345 3.68186743447416E-14 Biomarker Comparison Reference:  Biom Comparison: 1697531_1697496 Effect Metric:  0.702995985826875 Lower CI:  0.607491511847202 Upper CI:  0.813514833459933 LN Ef

ApoE (clone 26C11)

ALZANTIBODIES In initial testing on western blots, antibody 26C11 reacted with murine ApoE endogenously expressed by the BV2 microglial cell line. The antibody also stained ApoE associated with amyloid plaques in the brains of APPPS1 mice. Antibody 26C11 recognizes mou