343764 RESULTS
RESEARCH NEWS 2001-05-18 Research News The aggregating protein called agrin is a component of two quite different types of synapses: synapses in the neuromuscular junction and the immunological synapse between T cells and antigen-presenting cells. In both systems, membrane protei
RESEARCH NEWS 2001-05-18 Research News The Journal of Alzheimer's Disease has awarded the 2001 Alzheimer Medal to Luciano D'Adamio for his article, "Generation of an apoptotic intracellular peptide by γ-secretase cleavage of Alzheimer's amyloid-β protein precu
RESEARCH NEWS 2001-05-17 Research News (From Nature press release.) Permanent memories are thought to be stored in the cortex, but little is known about the processes that incorporate memories into cortical networks. Now [in today's Nature] Alcino J. Silva of the University
RESEARCH NEWS 2001-05-17 Research News (From Nature press release.) The path from identifying a genome sequence to pinpointing the contribution of each gene is beset with pitfalls. In a Brief Communication [in today's Nature], researchers describe discrepancies between what
COMMENT I have to admit that the emphasis in calcium signaling can be a useful way to solve the old controversy over the role of calcium in AD. Apparently, experimentalists have been assuming that the time scale of calcium signaling is the same as that of the ins
RESEARCH NEWS 2001-05-08 Research News Stem cells from the bone marrow of adults may be as flexible as embryonic stem cells, according a study in the current issue of Cell. Researchers at Yale, New York University, and Johns Hopkins found that these cells, which continuously repl
RESEARCH NEWS 2001-05-03 Research News Two reports in tomorrow's Science add to a growing body of evidence that glial cells play more than a "housekeeping" role and are essential for neuronal signalling (see also 26 January news). M. Iino and colleagues report that
RESEARCH NEWS 2001-05-03 Research News (From Science press release) In a prime example of what science can accomplish in the "post-genomic" era, researchers have pieced together the functions of a variety of genes involved in a yeast metabolism pathway. If an organism&#
RESEARCH NEWS 2001-05-01 Research News A closer look at mitochondria in Alzheimer's disease confirms that oxidative damage to these cellular power plants is a central feature of the disease, according to a report in the May 1 issue of the Journal of Neuroscience. The study,
RESEARCH NEWS 2001-04-25 Research News A major challenge for achieving nerve regeneration following an injury to the adult brain and spine is the presence of numerous proteins that block the growth of axons across the injury site. In tomorrow's Nature, James Fawcett and coll
RESEARCH NEWS 2001-04-12 Research News Researchers from France reported success in synthesizing novel compounds that specifically target γ-secretase cleavage of amyloid-β (Aβ) peptide, without affecting the enzyme's cleavage of other substrates such as Notch and possibly Ire
RESEARCH NEWS 2001-04-02 Research News Immune Network Ltd. reported last week that the company's Canadian Phase I clinical study has been halted due to an unexplained incidence of adverse findings in blood samples from healthy volunteers. Studies are now under way to investi
RESEARCH NEWS 2001-03-30 Research News (From Nature press release). Stem cells from mouse bone marrow can help repair muscle killed in heart attacks, Piero Anversa and his team at New York Medical College, New York, and colleagues, show in [the 5 April issue of] Nature. The resul
COMMUNITY NEWS 2001-03-27 Community News A team at Dartmouth College, New Hampshire, has developed a brain-image repository that will make it possible for scientists to freely share fMRI data with colleagues worldwide. The National Functional Magnetic Resonance Imaging (fMRI) Data
INTERVIEWS 2001-03-23 Interviews ARF: What is the hypothesis driving research in your lab? SG: We are investigating the role of signal transduction in regulating b amyloid generation; both the possibility (1) that changes in signalling contribute to disease-related changes in
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