11505 RESULTS
COMMENT This recent article by Minhas et al. should resonate as a wake-up call to all scientists and clinicians working on Alzheimer’s disease (AD) and other neurodegenerative pathologies. The article aptly demonstrates that in a variety of in vitro and in vivo e
COMMENT Reading these results about "cleaning Aβ" from the brains of demented patients using these new antibodies in clinical trials, a question comes to mind. I have read a new definition of "non-demented Alzheimer's patients" when they
COMMENT The story behind a Master … When I arrived at Neurosciences Group at the University of Antioquia, in the early 2000s, I was in my fifth semester of medicine. I met Francisco Lopera at a presentation and felt like the world had opened up to me, and I said
COMMENT I am very sad to hear of Francisco Lopera’s passing. Ken Kosik introduced me to Francisco because they wanted help in performing a genetic study in the families Francisco had identified. We collaborated for several years in the 1990s to identify the mutat
COMMENT Francisco had a profound impact on my work and on the broader research community. He consistently fostered collaborations and pushed the boundaries of what was possible. He set the standard for engaging with and supporting families affected by neurodegene
COMMENT I was honored to know Francisco Lopera as a collaborator, dear friend, and brilliant mind who profoundly influenced Latin American science. Working with him on numerous projects, including our ReDLat consortium, gave me an insight into his unwavering comm
COMMENT I am very saddened by the passing of my dear friend, mentor, and collaborator, Dr. Francisco Lopera. It was a privilege to have him as my mentor for the past ~26 years. I owe so much of who I am today to his unwavering support. I will miss him deeply! I j
COMMENT As translated from Spanish by Joseph Arboleda-Velasquez, I’d like to share my remarks at Dr. Lopera’s memorial service. Dr. Francisco Lopera, my very dear friend for over 50 years, professor, and travel companion in the comings and goings of life and scie
COMMENT Francisco was such a visionary and light in our field. We will deeply miss him. His kind approach, consummate devotion to his patients and families, and generous spirit brought so much progress and hope to his families and to all Alzheimer’s researchers—a
COMMENT Our relationship began in 2008, after Ken Kosik connected us to consider whether it was possible to conceive, fund and implement a prevention trial in ADAD. Alzforum captured several of the subsequent brainstorming meetings that we convened over the next
COMMENT Francisco Lopera: A Memory and a Tribute Autumn already! – But why regret an eternal sun if we are embarked on the discovery of divine light – far from all those who fret over seasons.—Arthur Rimbaud Farewell, Pacho. How grateful I am to have had a moment
COMMENT I have always been amazed by the impact of chance on our lives. Several coincidental events and unusual circumstances led me to meet Francisco Lopera at a crucial time in my life, when I was a pre-graduate medical student. He identified in me a deep yearn
COMMENT I met Dr. Lopera while I was a medical student at the University of Antioquia in Medellín, Colombia. At the time, I was at a crossroads, uncertain about continuing a career in medicine. Through my interactions with Dr. Lopera, I found my path as a physici
COMMENT This intriguing study shows that big tau has distinct physiological properties compared to the other, better-studied isoforms. The prevailing view that big tau is confined to the periphery is also shown to be incomplete. One question raised by the work is
COMMENT I was impressed with the quality and importance of this study and with the physiological and clinical implications of the results. It is worth noting that big tau has been understudied, despite indications of its possible relevance to degenerative disorde
