PAPER Leuchter MK, Oughli HA, Durbin KA, Jackson NJ, Elashoff D, Chang TS, Corlier J, Ngo D, Matthews C, Wong D, Fogel BL, Bitan G, Leuchter AF, Vossel K, Suthana N
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347694 RESULTS
PAPER Liu GS, Song Y, Yan JS, Chai YJ, Zhao YF, Ma H
Identification of enterotype for patients with Alzheimer's disease.
J Transl Med. 2025 Mar 10;23(1):299. PubMed.PAPER Lv L, Zhang H, Tan J, Wang C
Neuroprotective role and mechanistic insights of DJ-1 dimerization in Parkinson's disease.
Cell Commun Signal. 2025 Mar 10;23(1):129. PubMed.PAPER Cai Y, Kanyo J, Wilson R, Bathla S, Cardozo PL, Tong L, Qin S, Fuentes LA, Pinheiro-de-Sousa I, Huynh T, Sun L, Mansuri MS, Tian Z, Gan HR, Braker A, Trinh HK, Huttner A, Lam TT, Petsalaki E, Brennand KJ, Nairn AC, Grutzendler J
Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer's disease.
Nat Aging. 2025 Mar 10; Epub 2025 Mar 10 PubMed.PAPER Bian X, Guo Q, Yau LF, Yang L, Wang X, Zhao S, Wu S, Qin X, Jiang ZH, Li C
Berberine-inspired ionizable lipid for self-structure stabilization and brain targeting delivery of nucleic acid therapeutics.
Nat Commun. 2025 Mar 10;16(1):2368. PubMed.PAPER Dahiya M, Yadav M, Goyal C, Kumar A
Insulin resistance in Alzheimer's disease: signalling mechanisms and therapeutics strategies.
Inflammopharmacology. 2025 Mar 10; Epub 2025 Mar 10 PubMed.PAPER Qaisar R, Karim A, Iqbal MS, Alkahtani SA, Ahmad F
Associations of plasma Neurofilament light chain with sarcopenia and physical capacity in patients with Alzheimer's diseases.
Acta Neurol Belg. 2025 Mar 11; Epub 2025 Mar 11 PubMed.PAPER Xiao Y, Zhang M, Lu N
Fluorescent Fingerprint Identification of Protein Structural Changes and Disease-Specific Amyloid Beta Aggregates Based on a Single-Nanozyme Sensor Array.
Anal Chem. 2025 Mar 11;97(9):4978-4986. Epub 2025 Feb 25 PubMed.PAPER Pollock JM, Yew CH, Tripathi A
Utilizing Functionalized Dual-Microbead Interfaces for Measurements of Amyloid-beta (1-42) with Femtomolar Sensitivity.
Langmuir. 2025 Mar 11;41(9):5870-5876. Epub 2025 Feb 24 PubMed.PAPER Liu J, Chen L, Zhang ZL, Wen W, Zhang X, Wu Z, Wang S
Nano-Collision Electrochemistry for Real-Time Monitoring of Amyloid-β Oligomerization and Rapid Screening of Degrading Drugs.
Anal Chem. 2025 Mar 11;97(9):4898-4905. Epub 2025 Feb 24 PubMed.PAPER Wu Y, Xu R, Gasevic D, Yang Z, Yu P, Wen B, Liu Y, Zhou G, Zhang Y, Song J, Liu H, Li S, Guo Y
UK Biobank data demonstrate long-term exposure to floods is a risk factor for incident dementia.
Commun Med (Lond). 2025 Mar 10;5(1):71. PubMed.PAPER Tang M, Rong D, Gao X, Lu G, Tang H, Wang P, Shao NY, Xia D, Feng XH, He WF, Chen W, Lu JH, Liu W, Shen HM
A positive feedback loop between SMAD3 and PINK1 in regulation of mitophagy.
Cell Discov. 2025 Mar 11;11(1):22. PubMed.Robert Mach on A positron emission tomography tracer for the imaging of oxidative stress in the central nervous system.
COMMENT I congratulate the authors for trying to develop an alternative strategy to imaging reactive oxygen and reactive nitrogen species (ROS/RNS) in vivo with PET. Our group developed the radiotracer, [18F]ROStrace, and we have conducted PET imaging studies to
PAPER Gallagher E, Li S, Lee H, Xu H, Lee VMY, Mach RH, McManus MJ
Noninvasive Detection of Oxidative Stress in a Mouse Model of 4R Tauopathy via Positron Emission Tomography with [18F]ROStrace
Int. J. Mol. Sci. 2025 . International Journal of Molecular SciencesRisvodetinib
THERAPEUTICS Inhibikase Therapeutics, Inc. IkT-148009 Small Molecule alpha-synuclein Other Between February 2021 and January 2023, Inhibikase ran a Phase 1 single- and multiple-ascending-dose trial. The study enrolled 108 participants, and tested nine single doses fro
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