Nicola Fattorelli, Renzo Mancuso on C1q from Microglia Meddles in Neuronal Translation
COMMENT This exciting and thought-provoking work by Scott-Hewitt et al. uncovers a new intraneuronal function for the microglial secreted protein C1q. The authors performed C1q co-immunoprecipitation from synaptosomes isolated from developing, young adult, and ad