PAPER Bian X, Guo Q, Yau LF, Yang L, Wang X, Zhao S, Wu S, Qin X, Jiang ZH, Li C
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PAPER Tang M, Rong D, Gao X, Lu G, Tang H, Wang P, Shao NY, Xia D, Feng XH, He WF, Chen W, Lu JH, Liu W, Shen HM
A positive feedback loop between SMAD3 and PINK1 in regulation of mitophagy.
Cell Discov. 2025 Mar 11;11(1):22. PubMed.PAPER Dahiya M, Yadav M, Goyal C, Kumar A
Insulin resistance in Alzheimer's disease: signalling mechanisms and therapeutics strategies.
Inflammopharmacology. 2025 Mar 10; Epub 2025 Mar 10 PubMed.PAPER Qaisar R, Karim A, Iqbal MS, Alkahtani SA, Ahmad F
Associations of plasma Neurofilament light chain with sarcopenia and physical capacity in patients with Alzheimer's diseases.
Acta Neurol Belg. 2025 Mar 11; Epub 2025 Mar 11 PubMed.PAPER Xiao Y, Zhang M, Lu N
Fluorescent Fingerprint Identification of Protein Structural Changes and Disease-Specific Amyloid Beta Aggregates Based on a Single-Nanozyme Sensor Array.
Anal Chem. 2025 Mar 11;97(9):4978-4986. Epub 2025 Feb 25 PubMed.PAPER Pollock JM, Yew CH, Tripathi A
Utilizing Functionalized Dual-Microbead Interfaces for Measurements of Amyloid-beta (1-42) with Femtomolar Sensitivity.
Langmuir. 2025 Mar 11;41(9):5870-5876. Epub 2025 Feb 24 PubMed.PAPER Liu J, Chen L, Zhang ZL, Wen W, Zhang X, Wu Z, Wang S
Nano-Collision Electrochemistry for Real-Time Monitoring of Amyloid-β Oligomerization and Rapid Screening of Degrading Drugs.
Anal Chem. 2025 Mar 11;97(9):4898-4905. Epub 2025 Feb 24 PubMed.Robert Mach on A positron emission tomography tracer for the imaging of oxidative stress in the central nervous system.
COMMENT I congratulate the authors for trying to develop an alternative strategy to imaging reactive oxygen and reactive nitrogen species (ROS/RNS) in vivo with PET. Our group developed the radiotracer, [18F]ROStrace, and we have conducted PET imaging studies to
PAPER Gallagher E, Li S, Lee H, Xu H, Lee VMY, Mach RH, McManus MJ
Noninvasive Detection of Oxidative Stress in a Mouse Model of 4R Tauopathy via Positron Emission Tomography with [18F]ROStrace
Int. J. Mol. Sci. 2025 . International Journal of Molecular SciencesRisvodetinib
THERAPEUTICS Inhibikase Therapeutics, Inc. IkT-148009 Small Molecule alpha-synuclein Other Between February 2021 and January 2023, Inhibikase ran a Phase 1 single- and multiple-ascending-dose trial. The study enrolled 108 participants, and tested nine single doses fro
COYA 302
THERAPEUTICS Coya Therapeutics IL2 plus Abatacept Combination Other Inflammation In October 2021, an investigator-initiated, open-label study of COYA 302 began at the Houston Methodist Research Institute. The study planned to enroll 10 people with ALS, treat them ever
Giulia Albertini
VIB/KU LeuvenBelgium
PAPER Thayer JA, Petersen JD, Huang X, Hawrot J, Ramos DM, Sekine S, Li Y, Ward ME, Narendra DP
Novel reporter of the PINK1-Parkin mitophagy pathway identifies its damage sensor in the import gate.
bioRxiv. 2025 Feb 20; PubMed.PAPER Sharma V, Unjum Saqib BZ, Aran KR
Leptin as a potential neuroprotective target in Parkinson's Disease: Exploring its role in Neuroinflammation, oxidative Stress, and dopaminergic neurodegeneration.
Neuroscience. 2025 Mar 8;572:134-144. Epub 2025 Mar 8 PubMed.PAPER Jiang Y, Jin J, Piao Y, Yin Y, Tang L, Guan Q, Gao Y, Feng T, Wang Z
A simple and effective screening strategy for early multiple system atrophy diagnosis and α-Synuclein forms in erythrocytes.
Front Aging Neurosci. 2025;17:1533504. Epub 2025 Feb 21 PubMed.Current Filters
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