Grand Challenges in Parkinson’s Disease

CONFERENCE 2025-09-09 00:00:00-2025-09-10 00:00:00 Grand Rapids, Michigan 09 &#x2013 10 September 2025 View Conference Website 0

PAPER Kondo S, Yamamoto N, Murakami T, Okumura M, Mayeda A, Imaizumi K

Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA.

Genes Cells. 2004 Feb;9(2):121-30. PubMed.

PAPER Hutton M

Missense and splice site mutations in tau associated with FTDP-17: multiple pathogenic mechanisms.

Neurology. 2001 Jun;56(11 Suppl 4):S21-5. PubMed.

Andrew Stern on Does CSF Aβ Reflect Protofibril Concentration, Rather Than Plaques?

COMMENT This interesting paper follows 30 years of the highly reproduced finding that the quantity of Aβ extracted from AD cortex in aqueous buffer, and retained in the supernatant after centrifugation (here termed protofibrils), correlates better with cognitive

Postdoctoral fellow in Alzheimer’s Disease of functional genomics and human iPSC and chimeric modeling

JOB 2025-02-14 Employer Boston University Principal Investigator Julia TCW Contact Application documents Cover letter (required), CV with reference contact (required), major publications (optional), indicate your interest on projects under Any comments section or on the

PAPER O'Dowd S, Murray B, Roberts K, Cummins G, Magennis B, Lynch T

Pallidopontonigral degeneration: a deceptive familial tauopathy.

Mov Disord. 2012 Jun;27(7):817-9. PubMed.

PAPER Bahr M, Wintlend M, Mandel OR, Studer RL, Jonaitis EM, Alberson SF, Meyering E, Ryther B, Hellenbrand T, Kaminski N, Chin NA, Betthauser TJ, Christian BT, Johnson SC

Cognitive outcomes with AD tauopathy characterized by florquinitau PET

Alzheimers Dement. 2025 Jan 9;20(Suppl 2):e092841. PMCID: PMC11714911. . Alzheimer's & Dementia

Robert Litman

Georgetown University Medical School
United States

PAPER Zuckerman S, Zimran A, Szer J, Revel-Vilk S, Altarescu G

Preimplantation Genetic Testing (PGT) to Reduce the Risk for GBA-Related Parkinson's Disease: Expanding the Applications for Embryo Selection.

Int J Mol Sci. 2025 Jan 22;26(3) PubMed.

PAPER Picard F, Nonaka T, Belotti E, Osseni A, Errazuriz-Cerda E, Jost-Mousseau C, Bernard E, Conjard-Duplany A, Bohl D, Hasegawa M, Raoul C, Galli T, Schaeffer L, Leblanc P

Enhanced secretion of the amyotrophic lateral sclerosis ALS-associated misfolded TDP-43 mediated by the ER-ubiquitin specific peptidase USP19.

Cell Mol Life Sci. 2025 Feb 13;82(1):76. PubMed.

PAPER Patnana DP, Kanikaram SP, Kumar P, Cheerala VS, Sivaramakrishnan V, Tripathi P, Chandra BP

Simultaneous determination of polycyclic aromatic hydrocarbons, their derivatives, and phthalic acid esters bound to ambient PM2.5 during pre-summer season in Bengaluru, India, and potential effect on protein aggregation diseases.

Environ Sci Pollut Res Int. 2025 Feb 13; Epub 2025 Feb 13 PubMed.

PAPER Elyasi L, Rosenholm JM, Jahanshahi M, Jesmi F

The Effect of Picein on Inhibitory Avoidance Memory and Activity of Antioxidant Enzymes in Hippocampus of Male Rats with Scopolamine-Induced Injury.

Mol Neurobiol. 2025 Feb 13; Epub 2025 Feb 13 PubMed.

PAPER Etaka JC, Lu Y, Kang W, Salsbury FR Jr, Derreumaux P

Impact of Amidation on Aβ25-35 Aggregation.

J Phys Chem B. 2025 Feb 13; Epub 2025 Feb 13 PubMed.

PAPER Li J, Zong K, Wei C, Zhong Q, Yan H, Wang J, Li X

Design, synthesis, and biological activity of human glutaminyl cyclase inhibitors against Alzheimer's disease.

Bioorg Med Chem. 2025 Feb 8;120:118105. Epub 2025 Feb 8 PubMed.

PAPER Du H, Ma F, Cao Y, Bai M, Gao X, Yang Z, Xu Y, Yan Y

Bis(7)-harmine derivatives as potential multi-target anti-Alzheimer agents.

Front Chem. 2025;13:1545908. Epub 2025 Jan 29 PubMed.