CD11b /Mac-1α (M1/70)
BD Pharmingen
monoclonal
IgG2b ,κ
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 700 conj.)
-
Human, Mouse
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported
-
CD11b /Mac-1α (M1/70)
BD Pharmingen
monoclonal
IgG2b ,κ
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 647 conj.)
-
Human, Mouse
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported
-
CD11b /Mac-1α (M1/70)
BD Pharmingen
monoclonal
IgG2b ,κ
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 488 conj.)
-
Human, Mouse
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported
-
CD11b /Mac-1α (ICRF44/44)
BD Pharmingen
monoclonal
IgG1 ,κ
Mouse
(aqueous buffered solution, affinity purified, BSA, goat serum, azide)
-
Human
immunogen = Human monocytes
detects CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
-
CD11b /Mac-1α (ICRF44/44)
BD Pharmingen
monoclonal
IgG1 ,κ
Mouse
(liquid, affinity purified, aqueous buffered solution, azide, Pacific Blue™ conj.Also available APC-Cy™7 conj, #557754PE-Cy™5 conj, #555389PE-Cy™7 conj, #557743)
-
Human
immunogen = Human monocytes
reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
-
CD11b /Mac-1α (ICRF44/44)
BD Pharmingen
monoclonal
IgG1 ,κ
Mouse
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 488 conj.Also available Alexa Fluor® 700 conj, #557918)
-
Human
immunogen = Human monocytes
reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP
-
CD11b /Mac-1α (ICRF44/44)
BD Pharmingen
monoclonal
IgG1 ,κ
Mouse
(liquid, affinity purified, aqueous buffered solution, BSA, azide, R-PE conj.Also available Biotin Conj, #555387)
-
Human
immunogen = Human monocytes
reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
-
CD11b /Mac-1α (ICRF44/44)
BD Pharmingen
monoclonal
IgG1 ,κ
Mouse
(liquid, affinity purified, aqueous buffered solution, azide.Also available No azide/low endotoxin, #555385)
-
Human
immunogen = Human monocytes
reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
-
CD11b /Mac-1α (M1/70)
BD Pharmingen
monoclonal
IgG2b ,κ
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, APC-Cy7 conj.Also available PerCP-Cy5.5 conj, #550993PE-Cy™7 conj, #552850APC conj, #553312PE conj, #553311)
-
Human, Mouse
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported
-
CD11b /Mac-1α (M1/70)
BD Pharmingen
monoclonal
IgG2b ,κ
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Biotin conj.Also available FITC conj, #553310)
-
Human, Mouse
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported
-
CD11b /Mac-1α (M1/70)
BD Pharmingen
monoclonal
IgG2b ,κ
Rat
(aqueous buffered solution, affinity purified, azideAlso available No azide/low endotoxin, #553307, for IP, blocking)
-
Human, Mouse
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported
-
CD11b /Mac-1α (M1/70)
BD Pharmingen
monoclonal
IgG2b ,κ
Rat
(affinity purified, IHC diluent containing serum and azide)
-
Human, Mouse
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes
detects CD11b; stains the macrophages, granulocytes, dendritic cells, and NK cells
-
CD45 (IH-1)
AbD Serotec
monoclonal
IgG1
Mouse
(liquid, TBS, azide, protein A purifiedAlso available FITC conj.)
-
Guinea Pig
-
CD45 on all leucocytes; IPs proteins of 220, 210, 195 kDa from lymph node lymphocytes and proteins of 195, 130 and 170 kDa from thymocytes
-
CD45 (K252-1E4)
AbD Serotec
monoclonal
IgG1
Mouse
(liquid, FCS, supernate, TBS, azide, protein A purifiedAlso available FITC conj)
-
Pig
Immunogen = procine peripheral blood lymphocytes
all porcine leucocytes
-
CD45R (RA3-6B2)
AbD Serotec
monoclonal
IgG2a
Rat
(liquid, affinity purified IgG, PBS, azideSee list of conjugations)
-
Cat, Human, Mouse
immunogen = Murine leukaemia-induced pre-B tumour cells (RAW112)
reacts with mouse CD45R a form of the CD45 antigen expressed by B cells and lytically active subsets of NK cells and non-MHC restricted CTL's; immunoprecipitates the high molecular weight form of CD45 (220kD)
-
CD45 (IBL-3/16)
AbD Serotec
monoclonal
IgG1
Rat
(liquid, affinity purified IgG, TBS, azide)
-
Mouse
immunogen = purified B cells from mouse lymph nodes
reacts with CD45; enhances the MHC Class II induced cluster formation of mouse B cells
-
LDL Receptor
Novus Biologicals
polyclonal
Rabbit
(liquid, peptide affinity purified, PBS, glycerol, azide)
-
Human, Monkey, Mouse
immunogen = synthetic peptide made to an internal portion of the human LDLR protein (within residues 500-550)
specific for both unglycosylated and glycosylated forms of the LDL Receptor
-
LDL Receptor
Novus Biologicals
polyclonal
Rabbit
(liquid, affinity purified, PBS, glycerol, azideAlso availableBiotin, NBP1-06709BHRP, NBP1-06709HDylight 488, NBP1-06709GDylight 549, NBP1-06709RDylight 649, NBP1-06709C)
-
Human, Monkey, Mouse
immunogen = synthetic peptide made to an internal portion of the human LDLR protein (within residues 500-550)
specific for both unglycosylated and glycosylated forms of the LDL Receptor
-
LDL Receptor
Novus Biologicals
polyclonal
IgG
Rabbit
(liquid, peptide affinity purified, TBS, BSA, azide)
-
Human, Mouse, Rat
immunogen = synthetic peptide from murine LDL receptor amino acids 499-511 (SVADTKGVKRRTL)
specific for LDL Receptor
-
LDL Receptor, C-term (EP1553Y)
Novus Biologicals
monoclonal
IgG
Rabbit
(liquid, ascites, BSA, Tris, glycerol, azide)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresponding to residues on the C-terminus of human LDL receptor
specific for both isoforms of LDL receptor
-
LDL Receptor (EP1553Y)
Abcam
monoclonal
IgG
Rabbit
(liquid, supernatant, saline, glycerol, BSA, Tris-glycine, azide)
-
Human, Mouse, Rat
immunogen = synthetic peptide: corresponding to residues from the C-terminus of the human LDL receptor
recognizes the LDL Receptor
-
LDL Receptor
Abcam
polyclonal
IgG
Rabbit
(liquid, affinity purified, TBS, glycerol, BSA, azide)
-
Human, Mouse, Rat
immunogen = synthetic peptide: SVADTKGVKRRTL, corresponding to amino acids 499-511 of Mouse LDL Receptor
recognizes glycosylated and unglycosylated LDL Receptor
-
PAK2 CT
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human, Mouse, Rat
immunogen = a 14 amino acid peptide from near the C-terminus of human PAK2
detects PAK2
-
PAK4 phos Ser474
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide (RRKpSLVG) corresponding to human PAK4 with a phosphorylated site at Serine 474
detects PAK4
-
PAK-γ
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, BSA, azide)
-
Human, Mouse, Rat
immunogen = a synthetic peptide corresponding to the N-terminus of human PAK-γ protein
detects PAK-γ
-
PAK4 phos Ser474
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide (RRKpSLVG) corresponding to human PAK4 with a phosphorylated site at Serine 474
detects PAK4
-
PAK6
Anaspec
polyclonal
IgG
Rabbit
(liquid, purified, PBS, azide)
-
Human
immunogen = a 13 amino acid peptide from near the center of human PAK6
detects PAK6
-
PAK5
Anaspec
polyclonal
IgG
Rabbit
(liquid, purified, PBS, azide)
-
Human
immunogen = a 13 amino acid peptide from near the center of human PAK5
detects PAK5
-
PAK4 IN
Anaspec
polyclonal
IgG
Rabbit
(liquid, purified, PBS, azide)
-
Human
immunogen = a 13 amino acid peptide from near the center of human PAK4
detects PAK4
-
α-Synuclein
Anaspec
monoclonal
IgG2a ,κ
Mouse
(liquid, ascites, protein-A purified, PBS, BSA, azide)
-
Human
immunogen = human recombinant synuclein-α
detects α-Synuclein
-
α-synuclein phos Ser87
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide (GAG-pS-IAA) corresponding to human α-Synuclein at the phosphorylated serine 87
detects α-synuclein
-
β-synuclein
Anaspec
polyclonal
Rabbit
(liquid, affinity purified, PBS, BSA, azide)
-
Human, Rat
immunogen = a synthetic peptide corresponding to near the C-terminus of human Synuclein-β
detects β-synuclein
-
Synuclein, pan
Anaspec
polyclonal
Rabbit
(liquid, affinity purified, PBS, BSA, azide)
-
Human, Rat
immunogen = a synthetic peptide corresponding to near the N-terminus of human α/β/γ-Synuclein protein
detects Synuclein
-
α-synuclein phos Ser87
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide (GAG-pS-IAA) corresponding to human α-Synuclein at the phosphorylated serine 87
detects α-synuclein
-
α-synuclein (paired 87)
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide (GAG-S-IAA) corresponding to human α-Synuclein protein surrounding serine 87
detects α-synuclein
-
Tau
Abcam
polyclonal
IgG
Rabbit
(liquid, PBS, glycerol, azide, affinity purified)
-
Human, Mouse, Rat
immunogen = synthetic non-phosphopeptide derived from human Tau around the phosphorylation site of Threonine 181.
detects endogenous levels of total Tau protein
-
Tau phos Thr181
Abcam
polyclonal
IgG
Rabbit
(liquid, PBS, glycerol, azide, affinity purified)
-
Human, Mouse, Rat
immunogen =synthetic phospho-peptide derived from human Tau around the phosphorylation site of threonine 181.
specific for Tau only when phosphorylated at threonine 181; ELISA for phospho-tau
-
Tau phos Thr205
Abcam
polyclonal
IgG
Rabbit
(serum, affinity purified, glycerol, PBS, saline, azide)
-
Human, Mouse, Rat
immunogen = a synthesized phosphopeptide derived from human Tau around the phosphorylation site of threonine 205 (P-G-TP-P-G)
specific for 62 kDa Tau only when phospho. at threonine 205
-
Tau (AT270)
Pierce Thermo Scientific
monoclonal
IgG1 κ
Mouse
(supernatant, affinity purified, no carrier or preservative, biotin conj.)
-
Human
immunogen == partially purified human PHF tau, aa. around phosphorylated Thr181
PHF tau, tamgles and neurofilaments; no cross with recomb. unphospho tau; weak cross with normal tau
-
Tau phospho 181P
Autogen Bioclear
kit
Mouse
(solid-phase enzymeimmunoassay, uses monoclonal HT7 for capture, AT270 biotin for incubation, streptavidin)
-
Human
-
specific for phospho tau in cerebrospinal fluid
-
tau (paired 181, 184)
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human, Mouse, Rat
immunogen = a synthetic peptide corresponding to human Tau surrounding the Threonine 181 and serine 184 region
detects tau
-
tau (paired 181, 184)
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human, Mouse, Rat
immunogen = a synthetic peptide corresponding to human Tau surrounding the Threonine 181 and serine 184 region
detects tau
-
tau phos Ser184
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide (TPP-pS-SGE) corresponding to human Tau at the phosphorylated site of Serine 184
detects the phosphorylated serine 184 of human Tau, not other phosphorylated sites or non-phosphorylated Tau
-
tau phos Ser184
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide (TPP-pS-SGE) corresponding to human Tau at the phosphorylated site of Serine 184
detects the phosphorylated serine 184 of human Tau, not other phosphorylated sites or non-phosphorylated Tau
-
tau phos Ser195
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide (SGDR-pS-GYSS) corresponding to human Tau at the phosphorylated site of Serine 195
detects phosphorylated serine 195 of human Tau, not other phosphorylated sites or non-phosphorylated Tau
-
tau phos Ser195
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide (SGDR-pS-GYSS) corresponding to human Tau at the phosphorylated site of Serine 195
detects phosphorylated serine 195 of human Tau, not other phosphorylated sites or non-phosphorylated Tau
-
tau (paired 231)
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human Tau surrounding the Threonine 231 region
detects human Tau
-
tau (paired 231)
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human Tau surrounding the Threonine 231 region
detects human Tau
-
tau (paired 409, 412, 413)
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human Tau surrounding amino acid residues 409, 412, and 413 region
detects human Tau
-
tau (paired 409, 412, 413)
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human Tau surrounding amino acid residues 409, 412, and 413 region
detects human Tau
-
tau phos Ser409
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide (RHL-pS-NVS) corresponding to human Tau at the phosphorylated site of Serine 409
detects phosphorylated serine 409 of human Tau, and weakly reacts with Tau (pSer412) and (pSer413).
-
tau phos Ser409
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide (RHL-pS-NVS) corresponding to human Tau at the phosphorylated site of Serine 409
detects phosphorylated serine 409 of human Tau, and weakly reacts with Tau (pSer412) and (pSer413).
-
tau phos Ser412
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic phosphopeptide (SNV-pS-STG) corresponding to human Tau at the phosphorylated site of Serine 412
detects phosphorylated serine 412 of human Tau, not other phosphorylated sites or non-phosphorylated Tau
-
tau phos Ser412
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic phosphopeptide (SNV-pS-STG) corresponding to human Tau at the phosphorylated site of Serine 412
detects phosphorylated serine 412 of human Tau, not other phosphorylated sites or non-phosphorylated Tau
-
SOX9 phos Ser181
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human SOX-9 at the phosphorylated Serine 181 (RRKpSVKN)
detects SOX9
-
SOX9 (paired Ser181)
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human, Mouse
immunogen = a synthetic peptide surrounding Serine 181 (RRKSVKN) of human SOX-9
detects SOX9
-
SOX9 phos Ser181
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human SOX-9 at the phosphorylated Serine 181 (RRKpSVKN)
detects SOX9
-
SOX9a/b (paired183)
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, MOPS, BSA, glycerol)
-
Zebra fish
immunogen = a synthetic peptide surrounding Serine 183 (RRKSVKN) of zebrafish SOX-9 a/b
detects SOX9
-
SOX9a/b phos Ser183
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, MOPS, BSA, glycerol)
-
Zebra fish
immunogen = a synthetic peptide corresponding to zebrafish SOX-9 a/b at the phosphorylated site of Serine 183 (RRKpSVKN)
detects SOX9
-
SREBP-1
Anaspec
monoclonal
IgG1 ,κ
Mouse
(liquid, protein-G purified, PBS, BSA, azide)
-
Human, Hamster
immunogen = a recombinant protein encoding the amino acids 301-407 of N-terminus (the bHLH/leucine zipper domain) of human SREBP-1
detects SREBP-1
-
SRF
Anaspec
polyclonal
Rabbit
(liquid, affinity purified, PBS, BSA, azide)
-
Human, Mouse, Rat
immunogen = a synthetic peptide corresponding to the C-terminus of human SRF
detects SRF
-
Stat3 phos Tyr705
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human STAT3 at the phosphorylation site of tyrosine 705 (SAAPpYLKTK)
detects Stat3
-
Stat3 phos Tyr705
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human STAT3 at the phosphorylation site of tyrosine 705 (SAAPpYLKTK)
detects Stat3
-
Stat3 (paired705)
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human STAT3 surrounding tyrosine705 (SAAPYLKTK)
detects Stat3
-
Stat3 phos Ser 727
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human STAT3 at the phosphorylation site of Serine 727 (DLPMpSPRTL)
detects Stat3
-
Stat3 (paired 727)
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human STAT3 surrounding serine 727 (DLPMpSPRTL)
detects Stat3
-
Stat3 phos Ser 727
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human STAT3 at the phosphorylation site of Serine 727 (DLPMpSPRTL)
detects Stat3
-
Stat3 phos Tyr705
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human
immunogen = a synthetic peptide corresponding to human STAT3 at the phosphorylation site of tyrosine 705 (SAAPpYLKTK)
detects Stat3
-
Stat3 CT
Anaspec
polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
-
Human, Mouse, Rat
immunogen = a synthetic peptide derived from the C-terminal region of human STAT3 protein
detects Stat3
-