Antibody

Apo-E

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: WU E4
Krul et al, Department of Medicine, Washington University School of Medicine, St. Louis
References:
Kim, 2009
Liu, 2007
Formulation: liquid, ascites, affinity purified
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = the major protein peak of apoHDL obtained
after G-200 chromatography

Specificity

binds to n-terminal end of ApoE CNBr fragment 5 (CB5)

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References

Paper Citations

  1. Kim J, Castellano JM, Jiang H, Basak JM, Parsadanian M, Pham V, Mason SM, Paul SM, Holtzman DM. Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance. Neuron. 2009 Dec 10;64(5):632-44. PubMed.
  2. Liu Q, Zerbinatti CV, Zhang J, Hoe HS, Wang B, Cole SL, Herz J, Muglia L, Bu G. Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron. 2007 Oct 4;56(1):66-78. PubMed.

External Citations

  1. Krul et al

Further Reading

No Available Further Reading