Sorrento: They’ve Just Got to Have It—Where’s That Biomarker? Part 1
This is part 1 of a biomarker update from Sorrento.
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Sorrento: They’ve Just Got to Have It—Where’s That Biomarker? Part 2
This is part 2 of the biomarker update from Sorrento.
Sorrento: More Fun, Less Amyloid for Transgenic Mice
If you need a reason to get off the bench and work up a sweat, consider this: Increasing physical and mental activity dramatically lowers amyloid plaque deposition in a mouse model of Alzheimer's disease...
Sorrento: Scientists Stop Clubbing, Start Tweaking, γ-Secretase
One of the surprises at the AD/PD 2005 conference held last week in Sorrento, Italy, lay in just how many groups presented new experimental therapy approaches in various stages of preclinical development.
Sorrento Secretase News: Baiting β, Awakening α
Spooked by the pitfalls of γ-secretase drug development, BACE fans like to point out that their aspartyl protease may be a safer target.
International Conference on Alzheimer's & Parkinson's Diseases 2005
Sorrento: Immunotherapy Update Hot Off Lectern of AD/PD Conference Sorrento: Scientists Stop Clubbing, Start Tweaking, γ-Secretase Sorrento Secretase News: Baiting β, Awakening α Sorrento: More Fun, Less Amyloid for Transgenic Mice Sorrento: They’ve Just
Sorrento: Immunotherapy Update Hot Off Lectern of AD/PD Conference
Yesterday, the 7th International Conference on Alzheimer’s and Parkinson’s disease—AD/PD 2005 for short—drew to a close in beautiful Sorrento, Italy...
Visualizing Success with MRI of Amyloid Plaques in Live Mice
Researchers from the RIKEN Brain Science Institute in Saitoma, Japan are reporting a new MRI-based method for identifying amyloid deposits...
Tamping Down Glutamate Receptors Cures Synapses in Fly Retardation Model
Treatment with glutamate receptor antagonists or lithium reverses behavioral defects, memory failure, and neuroanatomical abnormalities in...
How Many Neurons Does It Take to Form a Memory?
Memory loss is one of the most obvious and devastating symptoms of Alzheimer disease (AD). But despite advances in researchers’ understanding of...
Breaking Away—Neurodegeneration Caused by DNA Damage
Recent evidence has fingered DNA damage as a factor in neurodegeneration...
Cannabinoid Receptors and AD: Searching Beyond the Simple Story
Researchers from Spain describe changes in cannabinoid receptors in the brains of AD patients, as well as...
Statins and AD—What Role Isoprenoids?
There has been considerable excitement generated by findings that statins, which lower plasma cholesterol, may help protect against Alzheimer disease...
Varicose Axons: Traffic Jams Precede AD Pathology in Mice, Men
Early in the course of Alzheimer disease, blockages in axonal traffic lead to sick axons swollen with the jumbled pile-up of traffic components. The blockages precede...
Single (AD-Linked) Gene Causes Complex Behavior Phenotype
Having just brought you some news on the nurture half of the developmental equation, we flip the coin and examine...
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