Leonardo Tejo Gunawan
Hanyang UniversitySeoul, Korea, Republic of
SEARCH RESULTS
371 RESULTS
Phillip Janowicz on Fast Plaque Clearance with Little ARIA? So Teases Trontinemab at AD/PD 2024
COMMENT Firstly, I think these results are fantastic and show the possibilities of BBB-crossing immunotherapy. The big question I would have thought is, have the patients been cured? Moreover, or alternatively, if the patients had been treated in their 20s, 30s,
TREM1 Muddles Myeloid Cell Metabolism and Memory in Old Mice
RESEARCH NEWS 2024-03-21 Research News The macrophage and microglial receptor TREM1 whips up inflammation. In its tizzy, the receptor also perturbs myeloid cell metabolism and hastens cognitive decline in older wild-type mice and in two models of amyloidosis, according to scienti
Michal Schwartz on TREM1 Muddles Myeloid Cell Metabolism and Memory in Old Mice
COMMENT The paper by Wilson et al. is extremely timely and important. It attributes a key role to myeloid cells in coping with aging in general, and age-related neurodegenerative diseases in particular, with an emphasis on Alzheimer’s disease, focusing on trigger
Elizabeth Bradshaw, Kirstin Tamucci on TREM1 Muddles Myeloid Cell Metabolism and Memory in Old Mice
COMMENT This paper highlights, and raises questions about, potential crosstalk between the peripheral immune system and central nervous system microglia and how this communication could be a powerful modulator of neurodegeneration. While the authors found very sm
PAPER Zhang C, Kan X, Zhang B, Ni H, Shao J
The role of triggering receptor expressed on myeloid cells-1 (TREM-1) in central nervous system diseases.
Mol Brain. 2022 Oct 22;15(1):84. PubMed: 36273145PAPER Andreasson KI, Wilson EN, Wang C, Xin M, Panchal M, Rabinowitz JD, Minhas PS, Swarovski MS, Benitez JA, Durairaj AS, Chaney A, Iweka CA, Buckwalter MS, Ennerfelt HE, Umans J, Huang J, Zera KA, McReynolds MR, Greicius MD, James ML, Mehta SS, LeGuen Y, Tan YJ, Zuckerman AJ, Blacher E, Gauba E, Serrano GE, Cropper H, Jain P, Liu Q
TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease models
bioRxiv2024.03.05.583562PAPER Topriceanu CC, Shah M, Webber M, Chan F, Shiwani H, Richards M, Schott J, Chaturvedi N, Moon JC, Hughes AD, Hingorani AD, O'Regan DP, Captur G
APOE ε4 carriage associates with improved myocardial performance from adolescence to older age.
BMC Cardiovasc Disord. 2024 Mar 21;24(1):172. PubMed: 38509472Ksenia Kastanenka on Do Sleep Rhythms Create Ion Waves That Rinse the Brain?
COMMENT Fantastic work by both groups. The work by Jonathan Kipnis and colleagues could provide an additional explanation for why we saw plaque clearance in APP/PS1 mice after optogenetic rescue of slow waves during sleep. kkastanenka_305846 0 Sleep restoration b
CLARITI Regulatory Coordinator
JOB 2024-03-21 Employer University of Wisconsin-Madison Contact See https://jobs.wisc.edu/jobs/clariti-regulatory-coordinator-madison-wisconsin-united-states for more details. Description This position will serve as the regulatory coordinator for a multisite consortiu
Postdoctoral research fellow focused on proteomics in neurodegenerative diseases
JOB 2024-03-21 Employer Lund University Principal Investigator Oskar Hansson Contact Niklas Mattsson-Carlgren, niklas.mattsson-carlgren@med.lu.se Read more about the position and apply here: https://lu.varbi.com/en/what:job/jobID:710972/ Description Lund University is