PAPER Chang YJ, Chen YR

The coexistence of an equal amount of Alzheimer's amyloid-β 40 and 42 forms structurally stable and toxic oligomers through a distinct pathway.

FEBS J. 2014 Jun;281(11):2674-87. Epub 2014 May 6 PubMed: 24720730

PAPER Roach EB, Bleiberg J, Lathan CE, Wolpert L, Tsao JW, Roach RC

AltitudeOmics: Decreased reaction time after high altitude cognitive testing is a sensitive metric of hypoxic impairment.

Neuroreport. 2014 Apr 9; PubMed: 24722229

PAPER Koutsis G, Karadima G, Kladi A, Panas M

Late-onset Huntington's disease: diagnostic and prognostic considerations.

Parkinsonism Relat Disord. 2014 Jul;20(7):726-30. Epub 2014 Mar 27 PubMed: 24721491

PAPER Brouillet E

The 3-NP Model of Striatal Neurodegeneration.

Curr Protoc Neurosci. 2014 Apr 10;67:9.48.1-9.48.14. PubMed: 24723322

PAPER Serrat R, Mirra S, Figueiro-Silva J, Navas-Pérez E, Quevedo M, López-Doménech G, Podlesniy P, Ulloa F, Garcia-Fernàndez J, Trullas R, Soriano E

The Armc10/SVH gene: genome context, regulation of mitochondrial dynamics and protection against Aβ-induced mitochondrial fragmentation.

Cell Death Dis. 2014 Apr 10;5:e1163. PubMed: 24722288

PAPER Robbins KL, Glascock JJ, Osman EY, Miller MR, Lorson CL

Defining the therapeutic window in a severe animal model of spinal muscular atrophy.

Hum Mol Genet. 2014 Apr 9; PubMed: 24722206

PAPER Robinson SW, Nugent ML, Dinsdale D, Steinert JR

Prion protein facilitates synaptic vesicle release by enhancing release probability.

Hum Mol Genet. 2014 Apr 28; PubMed: 24722203

PAPER van der Merwe C, Loos B, Swart C, Kinnear C, Henning F, van der Merwe L, Pillay K, Muller N, Zaharie D, Engelbrecht L, Carr J, Bardien S

Mitochondrial impairment observed in fibroblasts from South African Parkinson's disease patients with parkin mutations.

Biochem Biophys Res Commun. 2014 May 2;447(2):334-40. Epub 2014 Apr 8 PubMed: 24721425

PAPER Helvik AS, Engedal K, Benth JS, Selbæk G

A 52 month follow-up of functional decline in nursing home residents- degree of dementia contributes.

BMC Geriatr. 2014 Apr 10;14(1):45. PubMed: 24720782

PAPER Barash JA, West JK, DeMaria A Jr

Accuracy of administrative diagnostic data for pathologically confirmed cases of Creutzfeldt-Jakob disease in Massachusetts, 2000-2008.

Am J Infect Control. 2014 Jun;42(6):659-64. Epub 2014 Apr 12 PubMed: 24721779

European Parliament Passes Law to Open Trial Data

COMMUNITY NEWS 2014-04-12 Community News The European Parliament approved a long-awaited bill  that will unify clinical trial information into one European Union database and require trial investigators to publish summarized results publicly. The bill, which passed on April 2 with

Alzheimer’s Accountability Act Puts Price Tag on NAPA Goals

COMMUNITY NEWS 2014-04-12 Community News The United States’ National Plan to Address Alzheimer’s Disease  calls for an effective treatment by 2025, but notably, does not fund this goal (see Jan 2012 news story). The Alzheimer’s Accountability Act of 2014, a bill introduced in Cong

Jeffrey Tarrand

University of Texas
Houston, United States

Karen Rylander

Eden Prairie, United States

PAPER Basak I, Pal R, Patil KS, Dunne A, Ho HP, Lee S, Peiris D, Maple-Grødem J, Odell M, Chang EJ, Larsen JP, Møller SG

Arabidopsis AtPARK13, which confers thermotolerance, targets misfolded proteins.

J Biol Chem. 2014 May 23;289(21):14458-69. Epub 2014 Apr 9 PubMed: 24719325