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CONFERENCE 2024-08-19 00:00:00-2024-08-23 00:00:00 Chicago, Illinois 19 – 23 August 2024 No-cost opportunity for early career researchers in psychosocial care and public health. View Conference Website 0
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RESEARCH NEWS 2024-04-26 Research News Numerous studies have cast TREM2-expressing microglia as good guys in the Alzheimer’s brain, but new research suggests some play a darker role. In the April 18 Nature Neuroscience, researchers led by Michal Schwartz and Valery Krizhanovsky a
COMMENT This article serves to validate and confirm a series of findings from previous papers, highlighting the presence of senescent microglia in AD-like pathology and their DAM-like identity. Previous studies from our group, using the APP/PS1 model (Hu et al.,
COMMENT This insightful paper by the Schwartz lab delves into the analysis of microglia in Alzheimer’s disease (AD) and aging models, shedding light on intriguing findings. The key discovery revolves around identifying two distinct subsets of microglia within the
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COMMENT This is an exciting study by Juan Bonifacino’s group where they explored the regulation and importance of the BORC adaptor complex in axonal transport of lysosomes using new BORC-deficient iPSC-derived human neurons. Whereas the role of lysosomes has been
RESEARCH NEWS 2024-04-26 Research News To allow for the local translation of proteins that suit the ever-changing needs of the axon, neurons must ship transcripts from the soma to their outermost reaches. For thousands of these mRNAs, hitchhiking is their predominant mode of tran
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