How the Other Half Lives—Or the What, How, and Where of the AβPP Intracellular Domain

• 1 Comment

20 Sep 2002

situation may be more complex than that. In fact, a recent Cell paper (Baek et al.) suggests additional

Axonal Transport Hypothesis Moves On to Implicate Presenilin

• 1 Comment

17 Jun 2003

recently. Peter Klein Scott, we published a paper recently in JBC on PP1 dephosphorylation of serine

Ceramide and Cholesterol: Possible Connections Between Normal Aging of the Brain and Alzheimer’s Disease

15 Oct 2005

In a paper just published in the inaugural issue of the new journal, Alzheimer's &

Latest γ-Secretase Substrate Involved in Synaptic Stability, Autism?

02 Nov 2012

Press for opening access to these two papers for Alzforum readers: Suzuki K, Hayashi Y, Nakahara S,

Webinar: Cortex Aging Too Fast? Blame TMEM106B and Progranulin

10 Apr 2017

the open access paper here. On April 20, 2017, readers joined Abeliovich, Rhinn,  Rosa Rademakers,

Are Glia Active Participants in Neurodegenerative Disease?

• 1 Comment

05 Dec 2005

Ben Barres Wenan, Mike Sofroniew’s paper shows that reactive gliosis is important in keeping neurons

Alzheimer Presenilins in the Nuclear Membrane, Interphase Kinetochores, and Centrosomes Suggest a Role in Chromosome Segregation

20 Mar 1998

comments by using our Comments form at the bottom of the page. Paper under Discussion: Li JH, Xu M, Zhou H.

Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down's Syndrome Patients

28 May 1998

Leeuwen: Yes, we think. As indicated in the Science paper ref.30 we have found similar events outside the

How Cognitive Stimulation Might Protect Against Aβ Oligomers

20 Mar 2013

We thank Neuron for giving Alzforum readers temporary free access to this paper: Li S, Jin M, Zhang

Leaky Blood-Brain Barrier a Harbinger of Alzheimer's?

• 1 Comment

30 Jan 2015

to this paper.   Please send technical questions prior to the actual event to   contact@alzforum.org.

Deficiency of Presenilin 1 Inhibits the Normal Cleavage of the Transmembrane Domain of Amyloid Precursor Protein

30 Jan 1998

to submit additional comments by using our Comments form at the bottom of the page. Paper Under

The AD8: A Brief Screening Tool for Very Mild Dementia

25 May 2007

reported results of further evaluation of the AD8 interview in back-to-back papers in Archives of

Intraneuronal Aβ: Was It APP All Along?

20 Jun 2011

its role in AD pathogenesis. The Guest Moderator was David Holtzman. Paper Under Discussion.

Presenilin Loss of Function—Plan B for AD?

• 21 Comments

09 Mar 2007

a lively Alzforum discussion when Peter Davies initiated a conversation about a paper from Bart de

Good-Bye Overexpression, Hello APP Knock-in. A Better Model?

13 Apr 2014

thanks Nature Neuroscience for making Saido's  paper  freely available to Alzforum readers.    View