Webinar: Cortex Aging Too Fast? Blame TMEM106B and Progranulin
slowing down a person’s rate of biological aging—but how to find the requisite variants? In the April 26
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New Frontier: Developing Outcome Measures for Pre-dementia Trials
See questions answered by Suzanne Hendrix As researchers push into the frontier of early-stage and preventative Alzheimer's disease clinical trials, they will have to measure whether a drug works in people who do not have dementia yet. Traditional ou
Slow Aβ; Clearance Is ApoE4’s Modus Operandi in Late-Onset AD
David Holtzman — Posted 26 July 2011 Background Text by Gabrielle Strobel ApoE reigns supreme as the
Intraneuronal Aβ: Was It APP All Along?
2006 Apr 19;26(16):4277-88. Abstract Bayer TA, Schäfer S, Breyhan H, Wirths O, Treiber C, Multhaup G.
Two New Sets of Diagnostic Criteria—Which Is Right for Your Clinic?
On 19 April 2011, the National Institute on Aging (NIA) and the Alzheimer’s Association (AA) published new guidelines for the diagnosis of Alzheimer’s disease (AD) and its pre-dementia and preclinical phases (see ARF related news story on McKhann et al.,
Grasping the Shadow Force: Immune Cells in ALS
When two biological networks as complex as the nervous and immune systems cross paths, you know the interaction is not going to be simple. Add in neurodegeneration—such as amyotrophic lateral sclerosis—and it creates a web that will take many scientists t
Reimagining Alzheimer's Disease—Time for Bright New Ideas?
Alois Alzheimer made a major breakthrough when he discovered senile plaques in the brains of dementia patients, and his work ultimately led to the discovery of amyloid-β and to the amyloid cascade hypothesis. But that cascade is only part of a much bigger
Herpes Simplex and Alzheimer’s—Time to Think Again?
On Thursday, 24 February 2011, Ruth Itzhaki, University of Manchester, U.K.; Elisa Porcellini, University of Bologna, Italy; Luc Letenneur, INSERM, Bordeaux, France, and Richard Smeyne, St. Jude Children’s Research Hospital, Memphis, Tennessee, shared som
Untapped Resource? New Study to Boost Acceptance of CSF Analysis
indicated that the incidence of all LP complications is low. Led by Blennow, the study found that only 2.6
Together at Last, Top Five Biomarkers Model Stages of AD
In this Webinar, Clifford Jack gave a slide talk summarizing a staged biomarker model of the Alzheimer’s cascade, followed by a panel discussion with Chet Mathis, David Holtzman, Henrik Zetterberg, Paul Aisen, Keith Johnson, Giovanni Frisoni, Douglas Gala
Seeded Aggregation and Transmissible Proteopathy—Creepy Stuff Not Just for Prions Anymore?
26;102(17):6098-102. Abstract Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E,
Can We (Should We?) Develop “Smart Drugs” to Stave Off Age-Related Memory Loss?
On 26 February 2009, we held a Webinar/Live Discussion with a slide presentation by Scott Small
LOAD and eFAD—Different Diseases, Different Hypotheses?
26;60(4):534-42. Abstract 0 Thursday, March 5, 2009- 00:00 Alzheimer's Disease
Early Detection of Alzheimer Disease—A Virtual Town Hall Meeting
Reply by Douglas Galasko — Posted 26 July 2008 Confidence that early-stage AD patients indeed have AD is
Sports Concussions, Dementia, and APOE Genotyping: What Can Scientists Tell the Public? What’s Up for Research?
This live discussion was held on 26 June 2008 with Sam Gandy, Mount Sinai School of Medicine, New
Have a topic idea for a webinar? We would love to hear it. Send an email to webinars [at] alzforum [dot] org.
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