345049 RESULTS
ALZANTIBODIES This monoclonal antibody was generated against paired helical filaments isolated from an Alzheimer’s brain. It recognizes a discontinuous epitope formed when tau folds in a way that brings together its N-terminal and third repeat regions. This tau conform
ALZANTIBODIES This monoclonal antibody, generated against paired helical filaments isolated from the brains of Alzheimer’s patients, recognizes tau doubly phosphorylated at serines 396 and 404. Immuno-electron microscopy showed that the antibody binds to tau filaments
ALZANTIBODIES This monoclonal antibody recognizes a tau conformation that precedes the appearance of neurofibrillary tangles. Similar to monoclonal antibody MC-1, Alz-50 detects a discontinuous epitope that includes amino acids in tau’s N-terminal and third repeat regi
ALZANTIBODIES This monoclonal antibody, generated against paired helical filaments (PHFs) isolated from Alzheimer’s brains, recognizes tau phosphorylated at serine 202. CP-13 labels neurofibrillary tangles (NFTs), pretangles, neuropil threads, and dystrophic neurites i
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