21 RESULTS
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COMMENT From en route to AAIC: This is a very cool paper overall. It’s not totally new, but I really enjoyed reading this work, and the findings makes sense to me. 0 mathias.jucker
COMMENT I was never a member of the Don Price lab at JHU, but as a postdoctoral fellow at the Gerontology Research Center, NIA, in Baltimore, I visited often and worked closely with members of the lab. At that time, the lab included brilliant scientists such as L
COMMENT Interestingly, last year, in Maia et al., we have shown that in three different APP transgenic mice, Aβ deposition seems to be ruled distinctively. In the initial stage of amyloid build-up, increased processing of APP seems more relevant, and in the secon
COMMENT This is a very interesting paper that surely will stimulate discussions and further research in the field. The most convincing evidence for the suggested mechanism comes from in vitro microglia cultures using prelabeled α-synthetic synuclein. The hypothe
COMMENT This impressive new research from the Cambridge group supports previous NMR findings of Tycko and coworkers (Lu et al., 2013; Qiang et al., 2017) of a predominant Aβ structure in a particular AD brain. Using amyloid-binding dyes such as luminescent conjug
COMMENT These are interesting results. However, it is worth noting that such astrocytes have been described before, and some of the "vacuoles" are in fact polyglucosan bodies (Jucker et al., 1992; Jucker et al., 1994; comment on Baglietto-Vargas et al.,
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