PAPER Knörnschild F, Zhang EJ, Ghosh Biswas R, Kobus M, Chen J, Zhou JX, Rao A, Sun J, Wang X, Li W, Muti IH, Habbel P, Nowak J, Xie Z, Zhang Y, Cheng LL
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PAPER Wang M, Jin B, Jo J
Acute Restraint Stress Induces Long-Lasting Synaptic Enhancement by Inhibiting AMPK Activation in AD Model Mice.
CNS Neurosci Ther. 2025 Mar;31(3):e70335. PubMed.PAPER Lindberg A, Tong J, Zheng C, Mueller A, Kroth H, Stephens A, Mathis CA, Vasdev N
Radiosynthesis, In Vitro Characterization, and In Vivo PET Neuroimaging of [18F]F-4 for Tau Protein: A First-in-Human PET Study.
ACS Chem Neurosci. 2025 Mar 19;16(6):1182-1189. Epub 2025 Mar 10 PubMed.PAPER Han YL, Yin HH, Li C, Du J, He Y, Guan YX
Discovery of New Pentapeptide Inhibitors Against Amyloid-β Aggregation Using Word2Vec and Molecular Simulation.
ACS Chem Neurosci. 2025 Mar 19;16(6):1055-1065. Epub 2025 Feb 25 PubMed.PAPER Finsterer J
The reliability of the mini mental state examination and Montreal Cognitive Assessment for assessing cognitive impairment also depends on the type of cognitive deficits.
Rev Assoc Med Bras (1992). 2025;71(1):e20241310. Epub 2025 Mar 17 PubMed.PAPER Zhu L, Liu C, Wang Y, Zhu X, Wu L, Chen L, Zhou J, Wang F
METTL3/IGF2BP2/IκBα axis participates in neuroinflammation in Alzheimer's disease by regulating M1/M2 polarization of microglia.
Neurochem Int. 2025 Mar 17;186:105964. Epub 2025 Mar 17 PubMed.PAPER He X, Ma Y, Zhang N, Zhou C
Preparation and NMR characterization of Aβ peptides at pathological pH.
Protein Expr Purif. 2025 Mar 17;231:106704. Epub 2025 Mar 17 PubMed.PAPER Muguruma K, Takahashi T, Tagane Y, Nazere K, Hara N, Nakamori M, Yamazaki Y, Morino H, Maruyama H
Intracellular anionic substances cause tau liquid-liquid phase separation.
Biochem Biophys Res Commun. 2025 Apr 9;757:151605. Epub 2025 Mar 7 PubMed.PAPER Rajagopal VM, Gelfman S
Errors in the Huntington's disease gene accumulate slowly and then all at once.
Nature. 2025 Mar;639(8055):584-586. PubMed.PAPER Raj A, Torok J, Ranasinghe K
Understanding the complex interplay between tau, amyloid and the network in the spatiotemporal progression of Alzheimer's Disease.
Prog Neurobiol. 2025 Mar 17;:102750. Epub 2025 Mar 17 PubMed.PAPER Sullivan AC, Zuniga G, Ramirez P, Fernandez R, Wang CP, Li J, Davila L, Pelton K, Gomez S, Sohn C, Gonzalez E, Lopez-Cruzan M, Gonzalez DA, Parker A, Zilli E, de Erausquin GA, Seshadri S, Espinoza S, Musi N, Frost B
A Phase IIa clinical trial to evaluate the effects of anti-retroviral therapy in Alzheimer's disease (ART-AD).
NPJ Dement. 2025;1(1):2. Epub 2025 Mar 12 PubMed.PAPER Fatima G, Ashiquzzaman A, Kim SS, Kim YR, Kwon HS, Chung E
Vascular and glymphatic dysfunction as drivers of cognitive impairment in Alzheimer's disease: Insights from computational approaches.
Neurobiol Dis. 2025 Mar 17;208:106877. Epub 2025 Mar 17 PubMed.Global Science Scholars Fellowship
GRANT Wednesday, March 19, 2025- 4:30pm The Chan Zuckerberg Biohub Network and the Stellar Science Foundation The Global Science Scholars program is a postdoctoral fellowship of up to two years to conduct research in a world-class lab in Japan or the U.S. Resea
Nicolas Barthélemy on ALS or Alzheimer’s? Blood Phospho-Tau Could Mean Either
COMMENT My interpretation of this paper is that it accurately acknowledges the inherent complexities in interpreting blood p-tau biomarker data. Tau undergoes normal phosphorylation in both the central nervous system (CNS) and peripheral nervous system (PNS), wit
Shorena Janelidze on ALS or Alzheimer’s? Blood Phospho-Tau Could Mean Either
COMMENT This important and interesting work by Drs. Abu-Rumeileh, Otto, and colleagues examines changes in serum p-tau biomarkers in ALS. The study robustly replicated two previous papers showing higher levels of plasma p-tau181 in ALS than in controls (Cousins e
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