PAPER Jarchow MM, Driscoll I, Breidenbach BM, Cook NR, Gallagher CL, Johnson SC, Asthana S, Hermann BP, Sager MA, Blennow K, Zetterberg H, Carlsson CM, Kollmorgen GC, Quijano-Rubio C, Cook DB, Dubal DB, Okonkwo OC

Older more fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles

medRxiv2025.02.27.25323056 .

US-Israel Alzheimer’s Disease Conference

CONFERENCE 2025-06-05 00:00:00-2025-06-05 00:00:00 Tel Aviv, Israel 05 June 2025 View Conference Website 0

Zeyu Zhu

Shahid Zaman on By Cleaving GABA(A) Receptors, BACE1 Lifts Lid on Hyperactivity

COMMENT A while back, we sought to characterize the electrophysiological phenotypes in one of the earliest presenilin transgenic mouse models (Zaman et al., 2000). LTP was enhanced in hippocampi of these mice, and this phenotype could be normalized with the use o

Neda Ieva Biliute

University of Strasbourg
France

Fangjia Yang

PAPER Yang J, Pu YL, Pan QL, Wang L, Li CL, Xie XY, Chen X, Li XY, Bai DQ, Zhu BL, Chen GJ

CPNE7 Regulates Amyloidogenesis Through CAP1-Dependent ADAM10 Translation.

J Neurochem. 2025 Mar;169(3):e70026. PubMed.

PAPER Afzal O, Alamri MA, Altharawi A, Alossaimi MA, Mohamed MA, Altamimi AS, Asfour HZ, Alhakamy NA, Firoz A

Rational design, docking, simulation, synthesis, and in vitro studies of small benzothiazole molecules as selective BACE1 inhibitors.

J Biomol Struct Dyn. 2025 Mar 2;:1-12. Epub 2025 Mar 2 PubMed.

PAPER PLOS One Editors

Retraction: TOM40 Mediates Mitochondrial Dysfunction Induced by α-Synuclein Accumulation in Parkinson's Disease.

PLoS One. 2025;20(3):e0319935. Epub 2025 Mar 3 PubMed. Retracted paper.

PAPER Saraiva MA

Determination of the size parameters of α-synuclein amyloid precursor forms through DLS analysis.

Eur Biophys J. 2025 Mar 3; Epub 2025 Mar 3 PubMed.

PAPER Taguchi K, Watanabe Y, Tanaka M

SENP2-based N-terminal truncation of α-synuclein in Lewy pathology propagation.

iScience. 2025 Feb 21;28(2):111935. Epub 2025 Jan 31 PubMed.

PAPER Elbatrawy AA, Ademoye TA, Alnakhala H, Tripathi A, Zhu X, Plascencia-Villa G, Perry G, Dettmer U, Fortin JS

Inspecting the Triazole Scaffold as Powerful Antifibril Agents against 2N4R Tau and α-Synuclein Aggregates.

ACS Omega. 2025 Feb 25;10(7):6721-6734. Epub 2025 Feb 12 PubMed.

PAPER Szegvari E, Holec SA, Woerman AL

Limitations and Applications of Rodent Models in Tauopathy and Synucleinopathy Research.

J Neurochem. 2025 Mar;169(3):e70021. PubMed.

PAPER Abdi IY, Hashish SA, El-Agnaf OA

Seeding amplification assay: Limitations and insights for enhanced clinical and research applications.

J Parkinsons Dis. 2025 Mar 2;:1877718X251325124. Epub 2025 Mar 2 PubMed.

PAPER Huang YT, Yang TJ, Liu KC, Chen MC, Chan PS, Chen JC

Intranasal α-Synuclein Induces Progressive Behavioral Impairments in Mice.

Behav Brain Res. 2025 Feb 28;:115517. Epub 2025 Feb 28 PubMed.