PAPER Kim C, Hovakimyan A, Zagorski K, Antonyan T, Petrushina I, Davtyan H, Chailyan G, Hasselmann J, Iba M, Adame A, Rockenstein E, Szabo M, Blurton-Jones M, Cribbs DH, Ghochikyan A, Masliah E, Agadjanyan MG

Retraction Note: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies.

NPJ Vaccines. 2025 Mar 12;10(1):47. PubMed. Retracted paper.

PAPER Morrow CB, Kamath V, Dickerson BC, Eldaief M, Rezaii N, Wong B, McGinnis S, Darby R, Staffaroni AM, Lapid MI, Pascual B, Rojas JC, Masdeu JC, Tsapkini K, Huey ED, Fisher DW, Pantelyat A, Balaji A, Sah E, Litvan I, Rascovsky K, Ghoshal N, Domoto-Reilly K, Kornak J, Onyike CU, ALLFTD Consortium

Neuropsychiatric symptoms cluster and fluctuate over time in behavioral variant frontotemporal dementia.

Psychiatry Clin Neurosci. 2025 Mar 13; Epub 2025 Mar 13 PubMed.

PAPER Songhori N, Goushky MS, Khaleghi MM, Mojerloo M, Sadeghi M, Mozafar M, Aghdam ZB, Ghajar M, Kianifar Y, Karimzadeh F, Khosravi F, Mayeli M

Growth-Associated Protein 43 Levels in the Cerebrospinal Fluid Correspond to the Cerebral Blood Flow Alterations in Alzheimer's Dementia Continuum: An Original Study.

Health Sci Rep. 2025 Mar;8(3):e70534. Epub 2025 Mar 11 PubMed.

PAPER Reyes-Pablo AE, Luna-Viramontes NI, Montiel-Sosa JF, Ontiveros-Torres MÁ, Garcés-Ramírez L, de la Cruz-López F, Apátiga-Pérez R, Villanueva-Fierro I, Hernandes-Alejandro M, Jaramillo-Loranca BE, Vargas-Hernández G, Pacheco-Herrero M, Luna-Muñoz J

Vulnerability of the entorhinal cortex II to neurodegeneration in Alzheimer's disease.

Brain Commun. 2025;7(2):fcaf091. Epub 2025 Feb 26 PubMed.

PAPER Abbott V, Housden BE, Houldsworth A

Could immunotherapy and regulatory T cells be used therapeutically to slow the progression of Alzheimer's disease?

Brain Commun. 2025;7(2):fcaf092. Epub 2025 Feb 25 PubMed.

PAPER Yu X, Zhu K, Wang T, Li HY, Zhang X, Zhong X, Wang L

The Correlation Between RIN3 Gene Methylation and Cognitive Impairment in Parkinson's Disease.

Neuropsychiatr Dis Treat. 2025;21:511-524. Epub 2025 Mar 7 PubMed.

PAPER Salemme S, Lombardo FL, Lacorte E, Sciancalepore F, Remoli G, Bacigalupo I, Piscopo P, Zamboni G, Rossini PM, Cappa SF, Perani D, Spadin P, Tagliavini F, Vanacore N, Ancidoni A

The prognosis of mild cognitive impairment: A systematic review and meta-analysis.

Alzheimers Dement (Amst). 2025;17(1):e70074. Epub 2025 Mar 12 PubMed.

Aurore Delvenne on With Age, Macrophages Chew up the Blood-CSF Barrier

COMMENT The mechanisms underlying the disruption of the choroid plexus in aging and age-related neurodegenerative diseases remain relatively underexplored. In this insightful study, Chen et al. provide compelling evidence that macrophage activity plays a crucial

Tord Labuda

Alzinova AB
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Stefan Pierrou

Alzinova AB
, Sweden

PAPER Alldred MJ, Ibrahim KW, Pidikiti H, Lee SH, Heguy A, Chiosis G, Mufson EJ, Stutzmann GE, Ginsberg SD

Profiling hippocampal neuronal populations reveals unique gene expression mosaics reflective of connectivity-based degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.

Front Mol Neurosci. 2025;18:1546375. Epub 2025 Feb 26 PubMed.

PAPER Sohur US, Gray DL, Duvvuri S, Zhang Y, Thayer K, Feng G

Phase 1 Parkinson's Disease Studies Show the Dopamine D1/D5 Agonist PF-06649751 is Safe and Well Tolerated.

Neurol Ther. 2018 Dec;7(2):307-319. Epub 2018 Oct 25 PubMed.

PAPER Gray DL, Allen JA, Mente S, O'Connor RE, DeMarco GJ, Efremov I, Tierney P, Volfson D, Davoren J, Guilmette E, Salafia M, Kozak R, Ehlers MD

Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor.

Nat Commun. 2018 Feb 14;9(1):674. PubMed.

Richard Ransohoff on With Age, Macrophages Chew up the Blood-CSF Barrier

COMMENT This paper focuses useful attention on the choroid plexus as a potential contributor to brain aging. The approach taken was to evaluate tight junctions of the CP epithelium, identifying claudin-1 (product of the CLDN1 gene) as declining in abundance with

PAPER Eyme KM, Sammarco A, Jha R, Mnatsakanyan H, Pechdimaljian C, Carvalho L, Neustadt R, Moses C, Alnasser A, Tardiff DF, Su B, Williams KJ, Bensinger SJ, Chung CY, Badr CE

Targeting de novo lipid synthesis induces lipotoxicity and impairs DNA damage repair in glioblastoma mouse models.

Sci Transl Med. 2023 Jan 18;15(679):eabq6288. Epub 2023 Jan 18 PubMed.