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Clinical characteristics of semantic variant of primary progressive aphasia with TDP-43- and tau-related gene variants.

J Alzheimers Dis. 2025 Feb;103(4):1090-1101. Epub 2025 Feb 9 PubMed.

PAPER Reardon S

A man was destined for early Alzheimer's- these genes might explain his escape.

Nature. 2025 Feb;638(8051):594. PubMed.

PAPER Patel M, Pottier C, Fan KH, Cetin A, Johnson M, Ali M, Liu M, Gorijala P, Budde J, Shi R, Cohen AD, Becker JT, Snitz BE, Aizenstein H, Lopez OL, Morris JC, Kamboh MI, Cruchaga C

Whole-genome sequencing reveals the impact of lipid pathway and APOE genotype on brain amyloidosis.

Hum Mol Genet. 2025 Feb 10; Epub 2025 Feb 10 PubMed.

PAPER Llibre-Guerra JJ, Fernandez MV, Joseph-Mathurin N, Bian S, Carter K, Li Y, Aschenbrenner AJ, Pottier C, Sigurdson W, McDade E, Gordon BA, Renton AE, Benzinger TL, Ibañez L, Barthelemy N, Johnson M, Hassenstab J, Wang G, Goate AM, Western D, Wang C, Hobbs D, Daniels A, Karch C, Morris JC, Cruchaga C, Johnson EC, Bateman RJ, Dominantly Inherited Alzheimer Network

Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia.

Nat Med. 2025 Feb 10; Epub 2025 Feb 10 PubMed.

PAPER Tian Q, Dong Q, Su Z, Liu Y, Ma L, Dong H, Xu Y, Ma Z, Chen X, Ma X

Association of body weight and serum uric acid with Alzheimer's disease biomarkers and cognitive impairment.

J Alzheimers Dis. 2025 Mar;104(1):255-268. Epub 2025 Feb 9 PubMed.

PAPER Zhang H, Zhou Z, Gu J, Lin Y, Yan Y, Chen X, Fan M, Huang Y

Genetic insights of lipid metabolism and lipid-lowering drugs with Lewy body dementia risk: Evidence from Mendelian randomization.

Prog Neuropsychopharmacol Biol Psychiatry. 2025 Mar 20;137:111282. Epub 2025 Feb 8 PubMed.

PAPER Ndukwe K, Serrano PA, Rockwell P, Xie L, Figueiredo-Pereira ME

Brain-penetrant histone deacetylase inhibitor RG2833 improves spatial memory in females of an Alzheimer's disease rat model.

J Alzheimers Dis. 2025 Mar;104(1):173-190. Epub 2025 Feb 9 PubMed.

PAPER Kumar WS, Bhutare SR, Sinha N, Issac TG, Alzheimer's Disease Neuroimaging Initiative *

Bayesian network modeling of statistical dependency within cognitive domains and clinical dementia severity ratings for Western and Indian cohorts.

J Alzheimers Dis. 2025 Mar;104(1):221-231. Epub 2025 Feb 9 PubMed.

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