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White-Matter Structural Connectivity and Alzheimer's Disease: A Mendelian Randomization Study.

Brain Behav. 2025 Feb;15(2):e70286. PubMed.

PAPER Shang J, Liu T, Gong W, Zhao Y

Exploring the bidirectional relationships between alzheimer's disease and cerebral small vessel disease: Insights from mendelian randomization.

J Stroke Cerebrovasc Dis. 2025 Apr;34(4):108259. Epub 2025 Feb 8 PubMed.

PAPER Ndukwe K, Serrano PA, Rockwell P, Xie L, Figueiredo-Pereira ME

Brain-penetrant histone deacetylase inhibitor RG2833 improves spatial memory in females of an Alzheimer's disease rat model.

J Alzheimers Dis. 2025 Feb 9;:13872877251314777. Epub 2025 Feb 9 PubMed.

PAPER Aman Y

Effect of cholinergic modulator in Parkinson's disease with cognitive impairment.

Nat Aging. 2025 Feb;5(2):177. PubMed.

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Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer's disease.

Nat Med. 2025 Feb;31(2):574-588. Epub 2025 Feb 10 PubMed.

PAPER Singh A, Maheshwari S, Yadav JP, Kumar R, Verma A, Singh S, Prajapati BG

Bioactive Compound-Fortified Nanocarriers in the Management of Neurodegenerative Disease: A Review.

Chem Biodivers. 2025 Feb 10;:e202402018. Epub 2025 Feb 10 PubMed.

PAPER VandeVrede L, Cho H, Sanderson-Cimino M, Wekselman F, Cobigo Y, Gorno-Tempini ML, Heuer HW, Kramer JH, Lario Lago A, Leichter D, Ljubenkov P, Miller BL, Perry DC, Rabinovici GD, Rojas JC, Rosen HJ, Saloner R, Staffaroni A, Triana-Baltzer G, Spina S, Seeley WW, Grinberg LT, Kolb HC, La Joie R, Boxer AL

Detection of Alzheimer Neuropathology in Alzheimer and Non-Alzheimer Clinical Syndromes With Blood-Based Biomarkers.

JAMA Neurol. 2025 Feb 10; Epub 2025 Feb 10 PubMed.

PAPER Park CH, Lee H, Lee YM, Lee BD, Moon E, Suh H, Kim K, Kim HJ, Shim H, Pak K, Choi KU, Kim CS

Sex-specific effects of apolipoprotein E ε4 genotype on longitudinal hippocampal atrophy in amnestic mild cognitive impairment over a 2-year evaluation period.

J Alzheimers Dis. 2025 Feb;103(4):1269-1276. Epub 2025 Feb 9 PubMed.

PAPER Ma Y, Tang C, Lei X, Wang L, He D

Clinical characteristics of semantic variant of primary progressive aphasia with TDP-43- and tau-related gene variants.

J Alzheimers Dis. 2025 Feb;103(4):1090-1101. Epub 2025 Feb 9 PubMed.

PAPER Reardon S

A man was destined for early Alzheimer's- these genes might explain his escape.

Nature. 2025 Feb;638(8051):594. PubMed.

PAPER Patel M, Pottier C, Fan KH, Cetin A, Johnson M, Ali M, Liu M, Gorijala P, Budde J, Shi R, Cohen AD, Becker JT, Snitz BE, Aizenstein H, Lopez OL, Morris JC, Kamboh MI, Cruchaga C

Whole-genome sequencing reveals the impact of lipid pathway and APOE genotype on brain amyloidosis.

Hum Mol Genet. 2025 Feb 10; Epub 2025 Feb 10 PubMed.

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Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia.

Nat Med. 2025 Feb 10; Epub 2025 Feb 10 PubMed.

Ling-Zhi Ma

Sydney Mason

University of Pennsylvania
United States