Joshua Emmerson

Washington University St Louis
Saint Louis, United States

Dhanya Mol

assistant professor on contract
Nadathara, India

In AD, Effects of Some Genetic Variants Limited to Cell Subtypes

RESEARCH NEWS 2024-03-27 Research News While genome-wide association studies tie variants to disease risk, they don’t explain how those variants influence gene expression or pathology. In the March 21 Nature Genetics, scientists led by Vilas Menon and Philip De Jager at New York’

PAPER Yang H, Kim J, Kim Y, Jang SW, Sestan N, Shim S

Cux2 expression regulated by Lhx2 in the upper layer neurons of the developing cortex.

Biochem Biophys Res Commun. 2020 Jan 22;521(4):874-879. Epub 2019 Nov 8 PubMed.

Darcy Adreon

University of Kentucky
Lexington, United States

Hillary Rouse

Steven Clapcote

University of Leeds
United Kingdom

PAPER Ohgita T, Sakai K, Fukui N, Namba N, Nakano M, Kiguchi Y, Morita I, Oyama H, Yamaki K, Nagao K, Kobayashi N, Saito H

Generation of novel anti-apoE monoclonal antibodies that selectively recognize apoE isoforms.

FEBS Lett. 2024 Apr;598(8):902-914. Epub 2024 Mar 26 PubMed.

PAPER Wang L, Qu F, Yu X, Yang S, Zhao B, Chen Y, Li P, Zhang Z, Zhang J, Han X, Wei D

Cortical lipid metabolic pathway alteration of early Alzheimer's disease and candidate drugs screen.

Eur J Med Res. 2024 Mar 25;29(1):199. PubMed.

PAPER Liu Y, Ritchie SC, Teo SM, Ruuskanen MO, Kambur O, Zhu Q, Sanders J, Vázquez-Baeza Y, Verspoor K, Jousilahti P, Lahti L, Niiranen T, Salomaa V, Havulinna AS, Knight R, Méric G, Inouye M

Integration of polygenic and gut metagenomic risk prediction for common diseases.

Nat Aging. 2024 Apr;4(4):584-594. Epub 2024 Mar 25 PubMed.

PAPER Xie Y, Ke X, Ye Z, Li X, Chen Z, Liu J, Wu Z, Liu Q, Du X

Se-methylselenocysteine ameliorates mitochondrial function by targeting both mitophagy and autophagy in the mouse model of Alzheimer's disease.

Food Funct. 2024 Apr 22;15(8):4310-4322. PubMed.

PAPER Velasco-Rodríguez LD, García HS, Rascón-Díaz MP

Curcumin and omega-3 polyunsaturated fatty acids as bioactive food components with synergistic effects on Alzheimer's disease.

Psychogeriatrics. 2024 May;24(3):701-718. Epub 2024 Mar 25 PubMed.

PAPER van Veluw SJ, Young MJ

Ethical considerations for the use of anti-amyloid immunotherapy in patients with early Alzheimer's disease.

Alzheimers Dement. 2024 May;20(5):3664-3665. Epub 2024 Mar 25 PubMed.

PAPER Zhu W, Zhou J, Shang L, Zhou Y, Wang Q, Yu Y, Dong L, Mao C, Chu S, Jin W, Li J, Gao J

Generation and characterization of an iPS cell line (PUMCi006-A) from skin fibroblasts of a patient with an M239T mutation in PSEN2 gene.

Stem Cell Res. 2024 Jun;77:103391. Epub 2024 Mar 14 PubMed.

PAPER Zhang J, Cui X, Zhao S, Chang Z, Zhang J, Chen Y, Liu J, Sun G, Wang Y, Liu Y

Establishment of a pharmacokinetics and pharmacodynamics model of Schisandra lignans against hippocampal neurotransmitters in AD rats based on microdi-alysis liquid chromatography-mass spectrometry.

Front Pharmacol. 2024;15:1342121. Epub 2024 Mar 11 PubMed.