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PAPER Horiuchi M, Watanabe S, Komine O, Takahashi E, Kaneko K, Itohara S, Shimada M, Ogi T, Yamanaka K
ALS-linked mutant TDP-43 in oligodendrocytes induces oligodendrocyte damage and exacerbates motor dysfunction in mice.
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Lycorine protects motor neurons against TDP-43 proteinopathy-induced degeneration in cross-species models with amyotrophic lateral sclerosis.
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Two cardinal features of ALS, reduced STMN2 and pathogenic TDP-43, synergize to accelerate motor decline in mice.
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Inflammatory cytokines disrupt astrocyte exosomal HepaCAM-mediated protection against neuronal excitotoxicity in the SOD1G93A ALS model.
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Seeding-competent TDP-43 persists in human patient and mouse muscle.
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Advancements in Targeting Ion Channels for the Treatment of Neurodegenerative Diseases.
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Co-Aggregation of TDP-43 with Other Pathogenic Proteins and Their Co-Pathologies in Neurodegenerative Diseases.
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Prion-like Spreading of Disease in TDP-43 Proteinopathies.
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Special Issue "Mechanisms and Novel Therapeutic Approaches for Neurodegenerative Diseases".
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Human VCP mutant ALS/FTD microglia display immune and lysosomal phenotypes independently of GPNMB.
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Upregulated miR-10b-5p as a potential miRNA signature in amyotrophic lateral sclerosis patients.
Front Cell Neurosci. 2024;18:1457704. Epub 2024 Nov 7 PubMed.Current Filters
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