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APOE4 genotype and aging impair injury-induced microglial behavior in brain slices, including toward Aβ, through P2RY12.

Mol Neurodegener. 2024 Mar 11;19(1):24. PubMed.

PAPER Liu Y, Cheng Y, Wen Y, Li C, Chen G, Li M

A case report of youth-onset lipoprotein glomerulopathy with APOE Chicago mutation.

BMC Nephrol. 2024 Mar 6;25(1):87. PubMed.

Ahmadreza Attarpour

University of Toronto
, Canada

Lisa Vermunt, Dea Gogishvili, Charlotte Teunissen on Neuroprotective Extracellular Matrix Seen in C9ORF72 ALS/FTD Models

COMMENT We have read the study from Milioto et al. with much interest, because last year we published a clinical study in which we made a similar observation (Gogishvili et al., 2023), namely that while TGF-β1 was increased in dementia compared to controls, it wa

HIV Drug Safe in Alzheimer’s Pilot Trial, Nudged Biomarkers

RESEARCH NEWS 2024-03-12 Research News Almost half of a person's DNA consists of retrotransposons, remnants of ancient viral infections that have jumped around the human genome. Retrotransposons are typically kept under wraps by epigenetics, but tau can unleash those restrai

Charles Zollinger

United States

PAPER Ramirez P, Sun W, KazempourDehkordi S, Zare H, Fongang B, Bieniek KF, Frost B

Nanopore-based DNA long-read sequencing analysis of the aged human brain

bioRxiv2024.02.01.578450 .

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