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Design, synthesis and biological evaluation of novel 6H-benzo[c]chromen-6-one, and 7,8,9,10-tetrahydro-benzo[c]chromen-6-one derivatives as potential cholinesterase inhibitors.

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A microdeletion in Alzheimer's disease disrupts NAMPT gene.

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PAPER Liu L, Niu L, Xu M, Han Q, Duan H, Dong M, Besenbacher F, Wang C, Yang Y

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ACS Nano. 2014 Sep 23;8(9):9503-10. Epub 2014 Sep 10 PubMed.

PAPER Sešok S, Bolle N, Kobal J, Bucik V, Vodušek DB

Cognitive function in early clinical phase huntington disease after rivastigmine treatment.

Psychiatr Danub. 2014 Sep;26(3):239-48. PubMed.

PAPER Lees R, Selvarajah J, Fenton C, Pendlebury ST, Langhorne P, Stott DJ, Quinn TJ

Test accuracy of cognitive screening tests for diagnosis of dementia and multidomain cognitive impairment in stroke.

Stroke. 2014 Oct;45(10):3008-18. Epub 2014 Sep 4 PubMed.

PAPER Payne BR, Stine-Morrow EA

Risk for Mild Cognitive Impairment Is Associated With Semantic Integration Deficits in Sentence Processing and Memory.

J Gerontol B Psychol Sci Soc Sci. 2014 Sep 4; PubMed.

Soheil Zadeh

Pfizer
United States

PAPER Aggad D, Vérièpe J, Tauffenberger A, Parker JA

TDP-43 toxicity proceeds via calcium dysregulation and necrosis in aging Caenorhabditis elegans motor neurons.

J Neurosci. 2014 Sep 3;34(36):12093-103. PubMed.

PAPER Spira AP, Chen-Edinboro LP, Wu MN, Yaffe K

Impact of sleep on the risk of cognitive decline and dementia.

Curr Opin Psychiatry. 2014 Nov;27(6):478-83. PubMed.

PAPER Falkowski J, Hynan LS, Womack KB, Hatanpaa KJ, White CL, Weiner MF

Does past or present depression differentiate Lewy body from Alzheimer disease?

Int Psychogeriatr. 2015 Apr;27(4):693-4. Epub 2014 Sep 4 PubMed.

PAPER Beauquis J, Vinuesa A, Pomilio C, Pavía P, Saravia F

[Hippocampal and cognitive alterations precede amyloid deposition in a mouse model for Alzheimer's disease].

Medicina (B Aires). 2014;74(4):282-6. PubMed.

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Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.

PLoS Genet. 2014 Sep;10(9):e1004606. Epub 2014 Sep 4 PubMed.

PAPER Nery LR, Eltz NS, Hackman C, Fonseca R, Altenhofen S, Guerra HN, Freitas VM, Bonan CD, Vianna MR

Brain intraventricular injection of amyloid-β in zebrafish embryo impairs cognition and increases tau phosphorylation, effects reversed by lithium.

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PAPER Guo J, Chang L, Zhang X, Pei S, Yu M, Gao J

Ginsenoside compound K promotes β-amyloid peptide clearance in primary astrocytes via autophagy enhancement.

Exp Ther Med. 2014 Oct;8(4):1271-1274. Epub 2014 Aug 6 PubMed.