Jürgen Götz on Aducanumab Approved to Treat Alzheimer’s Disease

COMMENT We are watching the approval of aducanumab with interest, given that we had cloned the antibody to evaluate whether a combination with therapeutic ultrasound would be more effective in clearing amyloid and improving cognitive functions in the APP23 mouse

Martin Ingelsson, Dag Sehlin on Double Whammy: APP Uppsala Deletion Ups Aβ and Its Aggregation Propensity

COMMENT We appreciate the insightful comment by Drs. Ezzat and Espay and are grateful that our colleagues noticed an incorrect statement with respect to the MS-based levels of Aβwt1-42, which were indeed lower in mutation carriers as compared to control subjects.

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