PAPER Niwa R, Zhou F, Li C, Slack FJ

The expression of the Alzheimer's amyloid precursor protein-like gene is regulated by developmental timing microRNAs and their targets in Caenorhabditis elegans.

Dev Biol. 2008 Mar 15;315(2):418-25. PubMed.

PAPER Zdanys K, Tampi RR

A systematic review of off-label uses of memantine for psychiatric disorders.

Prog Neuropsychopharmacol Biol Psychiatry. 2008 Aug 1;32(6):1362-74. PubMed.

PAPER Small DH

Network dysfunction in Alzheimer's disease: does synaptic scaling drive disease progression?

Trends Mol Med. 2008 Mar;14(3):103-8. PubMed.

PAPER Kröger E, Andel R, Lindsay J, Benounissa Z, Verreault R, Laurin D

Is complexity of work associated with risk of dementia? The Canadian Study of Health And Aging.

Am J Epidemiol. 2008 Apr 1;167(7):820-30. PubMed.

PAPER Shriner D, Baye TM, Padilla MA, Zhang S, Vaughan LK, Loraine AE

Commonality of functional annotation: a method for prioritization of candidate genes from genome-wide linkage studies.

Nucleic Acids Res. 2008 Mar;36(4):e26. PubMed.

PAPER Jack CR, Lowe VJ, Senjem ML, Weigand SD, Kemp BJ, Shiung MM, Knopman DS, Boeve BF, Klunk WE, Mathis CA, Petersen RC

11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment.

Brain. 2008 Mar;131(Pt 3):665-80. PubMed.

PAPER Reitz C, Tang MX, Manly J, Schupf N, Mayeux R, Luchsinger JA

Plasma lipid levels in the elderly are not associated with the risk of mild cognitive impairment.

Dement Geriatr Cogn Disord. 2008;25(3):232-7. PubMed.

PAPER Buggia-Prevot V, Sevalle J, Rossner S, Checler F

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

J Biol Chem. 2008 Apr 11;283(15):10037-47. PubMed.

PAPER Martin R, Griffith HR, Belue K, Harrell L, Zamrini E, Anderson B, Bartolucci A, Marson D

Declining financial capacity in patients with mild Alzheimer disease: a one-year longitudinal study.

Am J Geriatr Psychiatry. 2008 Mar;16(3):209-19. PubMed.

PAPER Jacova C, Peters KR, Beattie BL, Wong E, Riddehough A, Foti D, Scheltens P, Li DK, Feldman HH

Cognitive impairment no dementia- neuropsychological and neuroimaging characterization of an amnestic subgroup.

Dement Geriatr Cogn Disord. 2008;25(3):238-47. PubMed.

PAPER Gay BE, Taylor KI, Hohl U, Tolnay M, Staehelin HB

The validity of clinical diagnoses of dementia in a group of consecutively autopsied memory clinic patients.

J Nutr Health Aging. 2008 Feb;12(2):132-7. PubMed.

PAPER Shimmyo Y, Kihara T, Akaike A, Niidome T, Sugimoto H

Three distinct neuroprotective functions of myricetin against glutamate-induced neuronal cell death: involvement of direct inhibition of caspase-3.

J Neurosci Res. 2008 Jun;86(8):1836-45. PubMed.

Adam Bero

MIT
United States

Paul Coleman on Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease.

COMMENT It is interesting that this study found opposite effects of AD on telomere length in hippocampal cells versus white blood cells. 0 Paul_Coleman

Gwendolyn Wong on Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease.

COMMENT This captures the extraordinarily rapid growth of Aβ plaques in real time using sophisticated longitudinal multiphoton microscopy. Microglial cells are “caught in the act” of activation and recruitment. The data make for compelling watching, almost like w