Gianluigi Forloni on A Central Role for Prion Protein in Neurodegeneration?

COMMENT This paper by Corbett et al. is an interesting piece of science related to the possible key role played by cellular prion protein (PrPc) in the neurotoxicity exerted by oligomeric forms of amyloid-β, α-synuclein, and tau, which have pathogenic roles in Al

Gianluigi Forloni on Tracing Aβ’s Toxicity Through Prion Protein, Fyn Kinase

COMMENT This paper by the Strittmatter group describes a significant number of data; however, the relevance of these results remains unclear. All the in-vitro data are produced with short exposure to oligomers (15-20 minutes, sometimes hours). We do not know how

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Gianluigi Forloni on A Central Role for Prion Protein in Neurodegeneration?

Gianluigi Forloni on Tracing Aβ’s Toxicity Through Prion Protein, Fyn Kinase

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