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Correction: Clinical characterization of common pathogenic variants of SOD1-ALS in Germany.
J Neurol. 2025 Mar 8;272(4):259. PubMed. Corrected paper.Leon French on Sex Differences in Blood of Alzheimer’s and Parkinson’s Patients
COMMENT I commend Grandke et al. for highlighting that their strongest pathway-level signal, "SRP-dependent cotranslational protein targeting to membrane," aligns with the gingipain hypothesis. This pathway primarily comprises ribosomal proteins, e.g. R
PAPER Avey DR, Ng B, Vialle RA, Kearns NA, Lopes Kd, Iatrou A, Tissera SD, Vyas H, Saunders DM, Flood DJ, Xu J, Tasaki S, Gaiteri C, Bennett DA, Wang Y
Uncovering Plaque-Glia Niches in Human Alzheimer's Disease Brains Using Spatial Transcriptomics
bioRxiv2024.09.05.611566 .PSEN1 Q223K
MUTATIONS PSEN1 73659470 GRCh37/hg19 rs1898776259 C A 73192762 GRCh38/hg38 rs1898776259 C A Exon 7 Coding Increased Aβ42 levels and the Aβ42/Aβ40 ratio in cells. Unknown. Q223K Alzheimer's Disease: Not ClassifiedAlzheimer's Disease Detailed information on
PSEN1 W165L
MUTATIONS PSEN1 73653574 GRCh37/hg19 rs1898534725 G T 73186866 GRCh38/hg38 G T Exon 6 Coding Unknown, but predicted deleterious in silico (PHRED-scaled CADD score = 28.3). Unknown. W165L Alzheimer's Disease: Not ClassifiedAlzheimer's Disease Detailed info
Yizhou A. Liu
Washington University in St Louis School of Medicine
United States
PAPER Kshirsagar S, Islam MA, Reddy AP, Reddy PH
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CPST-GAN: Conditional Probabilistic State Transition Generative Adversarial Network With the Biomedical Large Foundation Models.
IEEE Trans Neural Netw Learn Syst. 2025 Feb 27;PP Epub 2025 Feb 27 PubMed.Current Filters
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