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Analysis of the causal relationship between five chosen factors and early-onset Alzheimer's disease: A Mendelian randomization study.

J Alzheimers Dis. 2025 Feb;103(4):1135-1149. Epub 2025 Feb 9 PubMed.

PAPER Bejaoui Y, Srour L, Qannan A, Oshima J, Saad C, Horvath S, Mbarek H, El Hajj N

The role of protective genetic variants in modulating epigenetic aging.

Geroscience. 2025 Feb 10; Epub 2025 Feb 10 PubMed.

PAPER Wang X, Shao X, Yu L, Sun J, Yin XS, Chen Z, Xu Y, Wang N, Zhang D, Qiu W, Liu F, Ma C

Changes in the pH value of the human brain in Alzheimer's disease pathology correlated with CD68-positive microglia: a community-based autopsy study in Beijing, China.

Mol Brain. 2025 Feb 10;18(1):10. PubMed.

PAPER

Novel Biomarkers of FTD-ALS.

Neuroscientist. 2025 Feb;31(1):6. PubMed.

Sutapa Das

PAPER Hassen S, Sgambato V

In Vivo Positron Emission Tomography Imaging of α-Synuclein: A Major Breakthrough.

Mov Disord. 2025 Feb 10; Epub 2025 Feb 10 PubMed.

PAPER Jang YJ, Kang SJ, Park HS, Lee DH, Kim JH, Kim JE, Kim DI, Chung CH, Yoon JK, Bhang SH

Drug delivery strategies with lipid-based nanoparticles for Alzheimer's disease treatment.

J Nanobiotechnology. 2025 Feb 10;23(1):99. PubMed.

PAPER Buscarnera S, Canevelli M, Bruno G, Garibotto V, Frisoni GB, Ribaldi F

Unraveling the link between frailty and Alzheimer's disease biomarkers in patients with mild cognitive impairment.

Geroscience. 2025 Feb 10; Epub 2025 Feb 10 PubMed.

PAPER Song H, Xia M, Zhao P, Yang J, Yu W

Overexpression of TGFBR3 Aggravates Cognitive Impairment and Neuroinflammation by Promoting Microglia M1 Polarization in the APP/PS1 Mouse Model of Alzheimer's Disease.

Mol Neurobiol. 2025 Feb 10; Epub 2025 Feb 10 PubMed.

PAPER Li KC, Shi HX, Li Z, You P, Pan J, Cai YC, Li JW, Ma XF, Zhang S, Diao L, Cai B, Wang HB, Chen L, Mao Y, Zhang X

Human DDIT4L intron retention contributes to cognitive impairment and amyloid plaque formation.

Cell Discov. 2025 Feb 11;11(1):12. PubMed.

PAPER Xiang JB, Wen W, Xu SJ

[Mechanism of Jiawei Xionggui Decoction in ameliorating cognitive impairment in APP/PS1 mice based on network pharmacology and metabolomics].

Zhongguo Zhong Yao Za Zhi. 2025 Jan;50(2):322-342. PubMed.

PAPER Zhang JF, Long QH, Zeng CH, Chen YM, Xie ZY, Cai YQ, Wang X

[Mechanism of Guben Jiannao Liquid on Alzheimer's disease by regulating autophagy based on LKB1/AMPK/mTOR pathway].

Zhongguo Zhong Yao Za Zhi. 2025 Jan;50(2):293-300. PubMed.

PAPER Hirabayashi S, Uyeda A, Manabe I, Yonezu Y, Saito T, Saido TC, Misawa H, Ogasawara Y, Kinoshita K, Muramatsu R

CCN1 derived from vascular endothelial cells impairs cognitive function in Alzheimer's disease model mice.

J Pharmacol Sci. 2025 Mar;157(3):146-155. Epub 2025 Jan 9 PubMed.

PAPER Piro-Gambetti B, Krinsky-McHale S, Kovacs C, Handen B, Christian B, Laymon CM, Minhas D, Luo W, Yoon DM, Fleming VL, Schworer E, Kirkorian H, Hartley SL, Alzheimer Biomarkers Consortium‐Down Syndrome

Eye Tracking as a Tool for Detecting Alzheimer's Disease in People With Down Syndrome.

J Intellect Disabil Res. 2025 Feb 10; Epub 2025 Feb 10 PubMed.

PAPER Haag L, Lancini E, Yakupov R, Ziegler G, Yi YJ, Lüsebrink F, Glanz W, Peters O, Spruth EJ, Altenstein S, Priller J, Schneider LS, Wang X, Preis L, Brosseron F, Roy-Kluth N, Fliessbach K, Wagner M, Wolfsgruber S, Kleineidam L, Ramirez A, Spottke A, Jessen F, Wiltfang J, Schneider A, Hansen N, Rostamzadeh A, Buerger K, Ewers M, Perneczky R, Janowitz D, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Heneka M, Dechent P, Hetzer S, Scheffler K, Düzel E, Betts MJ, Hämmerer D

CSF biomarkers are differentially linked to brain areas high and low in noradrenaline, dopamine and serotonin across the Alzheimer's disease spectrum.

Brain Commun. 2025;7(1):fcaf031. Epub 2025 Jan 23 PubMed.