PAPER Avey DR, Ng B, Vialle RA, Kearns NA, Lopes Kd, Iatrou A, Tissera SD, Vyas H, Saunders DM, Flood DJ, Xu J, Tasaki S, Gaiteri C, Bennett DA, Wang Y

Uncovering Plaque-Glia Niches in Human Alzheimer's Disease Brains Using Spatial Transcriptomics

bioRxiv2024.09.05.611566 .

PSEN1 Q223K

MUTATIONS PSEN1 73659470 GRCh37/hg19 rs1898776259 C A 73192762 GRCh38/hg38 rs1898776259 C A Exon 7 Coding Increased Aβ42 levels and the Aβ42/Aβ40 ratio in cells. Unknown. Q223K Alzheimer's Disease: Not ClassifiedAlzheimer's Disease Detailed information on

PSEN1 W165L

MUTATIONS PSEN1 73653574 GRCh37/hg19 rs1898534725 G T 73186866 GRCh38/hg38 G T Exon 6 Coding Unknown, but predicted deleterious in silico (PHRED-scaled CADD score = 28.3). Unknown. W165L Alzheimer's Disease: Not ClassifiedAlzheimer's Disease Detailed info

Yizhou A. Liu

Washington University in St Louis School of Medicine
United States

PAPER Saikusa K, Kinumi T, Kato M

Development of amyloid β (1-42) certified reference material NMIJ CRM 6210-a.

Anal Bioanal Chem. 2025 Mar 5; Epub 2025 Mar 5 PubMed.

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Targeting RPSA to modulate endosomal trafficking and amyloidogenesis in genetic Alzheimer's disease.

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Determinants for Substoichiometric Inhibition of IAPP and Aβ Amyloid Aggregations by Bri2 BRICHOS.

ACS Chem Neurosci. 2025 Mar 4; Epub 2025 Mar 4 PubMed.

PAPER Kshirsagar S, Islam MA, Reddy AP, Reddy PH

Cell culture research in aging and Alzheimer's disease: The strategic use/reuse of untreated controls and savings people's tax dollars.

J Alzheimers Dis Rep. 2025;9:25424823241310716. Epub 2025 Jan 15 PubMed.

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Gut microbiota may affect Alzheimer's disease through synaptic function mediated by CAMs pathway: A study combining Mendelian randomization and bioinformatics.

J Alzheimers Dis Rep. 2025;9:25424823241310719. Epub 2025 Jan 13 PubMed.

PAPER Klein BY, Ben-David I, Gofrit ON, Greenblatt CL

Repurposing peripheral immunocytes of Bacillus Calmette Guerin-vaccinated melanoma patients to reveal preventive Alzheimer's disease mechanisms, possibly via the unfolded protein response.

J Alzheimers Dis Rep. 2025;9:25424823241309664. Epub 2025 Feb 10 PubMed.

PAPER Ranganathan R, Li S, Sapozhnikov G, Wang S, Song YQ

Lower expression of BIN1's neuronal isoform in vulnerable excitatory neurons increases risk in Alzheimer's disease.

J Alzheimers Dis Rep. 2025;9:25424823241296018. Epub 2025 Jan 13 PubMed.

PAPER Sato K, Niimi Y, Ihara R, Iwata A, Nemoto K, Arai T, Higashi S, Igarashi A, Kasuga K, Iwatsubo T

Sentiment analysis of social media responses to the approval of lecanemab for the treatment of Alzheimer's disease in Japan.

J Alzheimers Dis Rep. 2025;9:25424823241307639. Epub 2025 Jan 15 PubMed.

PAPER Lee YJ, Gonzales E, Wu Y, Braun KL, Martin P, Willcox B, Andel R

The association between activities and cognitive health: Stratified analysis by APOE ε4 status.

J Alzheimers Dis Rep. 2024;8(1):1502-1515. Epub 2024 Nov 24 PubMed.

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Centella asiatica improves cognitive function and alters the hippocampal metabolome of aged Tg2576 and wild-type mice.

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PAPER Siriwardhana C, Carrazana E, Liow K, Chen JJ

Cardio and cerebrovascular diseases risk among Alzheimer's disease patients and racial/ethnic disparities, based on Hawaii Medicare data.

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