PAPER Mou Y, Zhang Y, Zheng Y, He G, Xu ZX, Xiao X, Ping Y

Intermittent Vibration Induces Sleep via an Allatostatin A-GABA Signaling Pathway and Provides Broad Benefits in Alzheimer's Disease Models.

Adv Sci (Weinh). 2025 Feb;12(5):e2411768. Epub 2024 Dec 10 PubMed.

PAPER Cheng R, Bai N, Liu S, Zhao X, Jiang B, Guo W, Cao S, Liu J, Li N, Li X, Wu X, Yi F, Wang Z, Guo Q, Wei J, Bai M, Jiang X, Song X, Wang Z, Miao Q, Wang D, Di Y, Liu H, Cao L

The deacetylase SIRT6 reduces amyloid pathology and supports cognition in mice by reducing the stability of APP in neurons.

Sci Signal. 2024 Dec 10;17(866):eado1035. Epub 2024 Dec 10 PubMed.

PAPER Zhao A, Cui E, Leroux A, Zhou X, Muschelli J, Lindquist MA, Crainiceanu CM

Objectively Measured Physical Activity Using Wrist-Worn Accelerometers as a Predictor of Incident Alzheimer's Disease in the UK Biobank.

J Gerontol A Biol Sci Med Sci. 2025 Jan 16;80(2) PubMed.

PAPER Fullam S, O'Dowd S, O'Connor A

Blood biomarkers of Alzheimer's disease: important considerations for use in clinical practice.

Neural Regen Res. 2025 Jan 1;20(1):205-206. Epub 2024 Apr 3 PubMed.

PAPER Singh V, Choudhury A, Ahn HJ

Fibrinogen's potential role in connecting cerebrovascular abnormalities with glymphatic dysfunction in Alzheimer's disease.

Neural Regen Res. 2025 Jan 1;20(1):203-204. Epub 2024 Apr 30 PubMed.

PAPER Benatar M, McDermott C, Turner MR, van Eijk RP

Rethinking phase 2 trials in amyotrophic lateral sclerosis.

Brain. 2024 Dec 6; Epub 2024 Dec 6 PubMed.

PAPER Benedetto G, Zannino C, Valente D, Covello R, Scalise S, Lucchino V, Quattrone A, Parrotta EI, Quattrone A, Cuda G

Generation of hiPSCs lines from three sporadic Parkinson's disease patients.

Stem Cell Res. 2025 Feb;82:103632. Epub 2024 Dec 10 PubMed.

PAPER Tamburrino L, Tafuri B, Gnoni V, Nigro S, Giugno A, Urso D, Zoccolella S, Filardi M, Logroscino G

Actigraphy validation in behavioral variant frontotemporal dementia.

Sleep Med. 2025 Feb;126:178-184. Epub 2024 Dec 10 PubMed.

PAPER Singh S, Khan S, Shahid M, Sardar M, Hassan MI, Islam A

Targeting tau in Alzheimer's and beyond: Insights into pathology and therapeutic strategies.

Ageing Res Rev. 2025 Feb;104:102639. Epub 2024 Dec 16 PubMed.

PAPER Arslan-Sarımehmetoğlu E, Gönen-Şentürk S

Evaluation of Depression and Perceived Voice Handicap Through Self-Report in Individuals With Alzheimer's Disease.

J Voice. 2024 Dec 13; Epub 2024 Dec 13 PubMed.

Yaning Wang on Is It Time to Approve Drugs Based on Amyloid Removal?

COMMENT I was the director of FDA’s Division of Pharmacometrics before I left FDA in 2021. In July this year, I watched the presentation by Dr. Kevin Krudys, Associate Director, Office of Neuroscience, CDER, FDA, titled "Recent Examples of Reasonably Likely

Jaoud Ansari

Jamia Millia Islamia
India

Tobias Madl on ‘MGWAS’ Ties Brain Metabolites to Alzheimer’s, Parkinson’s, More

COMMENT This publication presents a comprehensive genome-wide association study on brain and CSF metabolite levels, and reveals significant metabolic changes associated with various diseases, including Alzheimer’s. The authors have also developed a webserver that

PAPER Klein J

Membrane breakdown in acute and chronic neurodegeneration: focus on choline-containing phospholipids.

J Neural Transm (Vienna). 2000;107(8-9):1027-63. PubMed.

Dennis Selkoe on Is It Time to Approve Drugs Based on Amyloid Removal?

COMMENT We are grateful for the numerous comments to our 12-author Perspective that have been posted on Alzforum through December 12. They provide thoughtful analyses and critiques of our provocative proposal of full regulatory approval of new amyloid-lowering im