PAPER Malta SM, Rodrigues TS, Silva MH, Marquez AS, Ferreira RB, do Prado Mascarenhas FN, Zanon RG, Bernardes LM, Batista LL, da Silva MN, de Oliveira Santos D, Santos AC, Mendes-Silva AP, Spindola FS, Ueira-Vieira C
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Bidirectional interaction between IL and 17A/IL-17RA pathway dysregulation and α-synuclein in the pathogenesis of Parkinson's disease.
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The small molecule ZPD-2 inhibits the aggregation and seeded polymerisation of C-terminally truncated α-Synuclein.
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Gut microbial metabolism in Alzheimer's disease and related dementias.
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Exp Neurol. 2024 Oct 25;383:115029. Epub 2024 Oct 25 PubMed.SHR-1707
THERAPEUTICS Immunotherapy (passive) Amyloid-Related Two Phase 1 studies, in China and Australia, assessed safety and pharmacokinetics of SHR-1701 in healthy participants (Yang et al., 2024). In China, 50 young adults in five cohorts received 2, 6, 20, 40, or 60 mg/kg
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Participant-reported personal utility of genetic testing for Parkinson's disease and interest in clinical trial participation.
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Are rare heterozygous SYNJ1 variants associated with Parkinson's disease?
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DNA Methylation in Alzheimer's Disease.
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Tuning multispectral fluorescence quantum dot-based identification of short-length amyloid β peptides by applying Cu(II) ions.
Mikrochim Acta. 2024 Oct 26;191(11):700. PubMed.Current Filters
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