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338728 RESULTS

Saba Shahin


Cedars-Sinai Medical Center
Los ANgeles, United States

X-Chromosome-Wide Association Data Spot Alzheimer’s Loci

RESEARCH NEWS 2024-09-25 Research News About two-thirds of people with Alzheimer’s disease are women, yet due to the challenges in studying X chromosomes, a genetic foundation for this has been difficult to uncover. Now, two large X-chromosome-wide association studies (XWAS) and

PAPER Basilicata MF, Bruel AL, Semplicio G, Valsecchi CI, Aktaş T, Duffourd Y, Rumpf T, Morton J, Bache I, Szymanski WG, Gilissen C, Vanakker O, Õunap K, Mittler G, van der Burgt I, El Chehadeh S, Cho MT, Pfundt R, Tan TY, Kirchhoff M, Menten B, Vergult S, Lindstrom K, Reis A, Johnson DS, Fryer A, McKay V, DDD Study, Fisher RB, Thauvin-Robinet C, Francis D, Roscioli T, Pajusalu S, Radtke K, Ganesh J, Brunner HG, Wilson M, Faivre L, Kalscheuer VM, Thevenon J, Akhtar A

De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation.

Nat Genet. 2018 Oct;50(10):1442-1451. Epub 2018 Sep 17 PubMed.

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