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COMMUNITY NEWS 1998-02-23 Community News Scientists often complain that scientific journals take too long to review manuscripts, and that subscription prices are unaffordable. A new journal devoted to Alzheimer's disease research, Alzheimer's Reports, aims to carve out a
WEBINAR 1998-01-30 Deborah Watson and Kenneth Kosik led this live discussion on 30 January 1998. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Paper Under Discussion: De Strooper B, Saftig P, Craessaerts K, Vandersti
RESEARCH NEWS 1998-01-22 Research News Researchers trying to study the role of presenilin-1 (PS1) in Alzheimer's pathogenesis have been stymied by the fact that presenilin knockout mice die before birth. Bart De Strooper from the Flemish Institute of Biotechnology in Belgium
RESEARCH NEWS 1998-01-01 Research News Two recent papers describe the processes involved in the final stages of apoptotic cell death. During apoptosis, enzymes known as caspases break down cellular proteins, causing severe morphological changes and cell shrinkage. In the final st
RESEARCH NEWS 1997-12-18 Research News A pathologic form of prion protein is believed to cause scrapie, bovine spongiform encephalopathy and Creutzfeldt-Jakob disease. The normal function of prion protein is yet unknown, but a recent study by Hans Kretzschmar of the University of
RESEARCH NEWS 1997-12-18 Research News Why is the adult mammalian central nervous system unable to regenerate damaged axons? Scarring of glial tissue may be a factor, according to Jerry Silver and his colleagues at Case Western Reserve University School of Medicine. The researche
RESEARCH NEWS 1997-12-18 Research News An innovative microscope has been developed which provides scientists with a new window through which to explore the dynamics of molecular order and disorder in living cells and other quasi-liquid systems. Originally conceived by famed cell
RESEARCH NEWS 1997-11-24 Research News Researchers at California-based Affymetrix have analyzed the activity of every gene in the yeast genome in a single experiment using a new "DNA chip." This remarkable technological feat hints of a future, following completion of th
RESEARCH NEWS 1997-10-16 Research News Scientists working in Oxford University and Duke University Medical Center this week reported the discovery of two new genetic risk factors for late-onset Alzheimer’s disease. Nearly 90 percent of all Alzheimer's cases are late-onset, a
RESEARCH NEWS 1997-10-09 Research News A history of brain injury raises a person’s risk of Alzheimer’s disease, and many researchers now suspect that the brain’s inflammatory responses to injury may magnify the neurodegenerative process. Now researchers have identified a substanc
RESEARCH NEWS 1997-06-27 Research News Researchers in Dr. John Q. Trojanowski's lab at the University of Pennsylvania have discovered a new type of lesion in the brains of Alzheimer's patients. These new lesions appear only in brains with amyloid plaques, including brai
COMMUNITY NEWS 1997-06-26 Community News The National Library of Medicine's MEDLINE database is now accessible free to the general public through PubMed and Internet Grateful Med. Hot links to IGM and PubMed are available on the NLM home page. PubMed is an experimental search
RESEARCH NEWS 1997-04-29 Research News Put these two facts together: brain energy metabolism is abnormally low in Alzheimer's patients, and if your mother had Alzheimer's you are more likely to develop it than if your father had Alzheimer's. You might then logicall
RESEARCH NEWS 1997-04-24 Research News Results released today of a study published in the New England Journal of Medicine indicated that large doses of vitamin E may delay the time at which late-stage Alzheimer's patients must be institutionalized because of the loss of &quo
RESEARCH NEWS 1997-03-12 Research News An enormous extended family living in a rural community in Colombia could provide new insights into environmental and genetic factors contributing to Alzheimer’s disease. All family members who were diagnosed with the disease carried an iden
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